L. Scarnecchia

TL;DR: Serum TRAP activity is confirmed as a valid cytochemical marker for identification of osteoclasts, but is an osteoclastic marker of weak sensitivity due to known factors, such as synthesis of the enzyme not being unique to osteoclast, enzyme instability, and the presence of inhibitors in serum.

TL;DR: A significant inverse correlation between serum TRAP activity values and bone mineral density (BMD) measured both at an ultradistal radial point and at the lumbar spine is found.

TL;DR: The results of the present study emphasize the importance of 25-hydroxyvitamin D measurement, and the need to increase vitamin D intake in Italy; foodstuff fortification and supplement use must be considered in order to prevent negative effects of vitamin D deficiency on skeletal integrity.

TL;DR: The results show that IGF-I plasma levels decrease immediately after menopause, since significantly lower levels are reached in the first years, and correlations found between IGF-i levels and BMD suggest a possible role of reduced IGF- I in bone loss at particular skeletal sites.

TL;DR: Results show that prophylactic administration of salmon CT in ovariectomized women prevent estrogen deficiency-induced bone loss, inhibiting skeletal resorption and allowing osteogenesis to occur normally.