Showing papers by "L. Trevor Young published in 1998"

TL;DR: Downstream changes in the cAMP pathway may occur in patients with MDD and antidepressant treatment may be associated with a return to normal temporal cortex of CREB in patients, which suggests that the effects of antidepressants may be regional.

TL;DR: Women with BD have a later onset of mania, are more likely to have a rapid cycling course, experience mixed episodes, experience more depressive episodes and report more overall impairment in all MOS subscale scores with significant impairment in physical health and pain.

TL;DR: Differential effects of the two most commonly prescribed mood stabilizers used to treat BD on Fos/Jun protein levels and their AP-1 binding activity in human neuroblastoma SH-SY5Y cells suggest that both these mood stabilizer may have an effect on neuronal gene expression of target genes containing the AP- 1 consensus sequence in their promoter regions after acute treatment.