L
Lakshmi Radhakrishnan
Researcher at University of Pittsburgh
Publications - 15
Citations - 499
Lakshmi Radhakrishnan is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Medicine & Emergency department. The author has an hindex of 3, co-authored 3 publications receiving 340 citations.
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Journal ArticleDOI
Distribution of Brain HIV Load in AIDS
Clayton A. Wiley,Virawudh Soontornniyomkij,Lakshmi Radhakrishnan,Eliezer Masliah,John W. Mellors,Steve A. Hermann,Peter Dailey,Cristian L. Achim +7 more
TL;DR: Assessment of overall brain viral load requires careful attention to regional quantitation, and selective regions, including basal ganglia and hippocampus, showed higher levels of virus than the cerebellar cortex and mid‐frontal cortical gray matter.
Journal ArticleDOI
HIV mediates a productive infection of the brain.
Clayton A. Wiley,Cristian L. Achim,Cindy Christopherson,Yorda Kidane,Shirley Kwok,Eliezer Masliah,John W. Mellors,Lakshmi Radhakrishnan,Guoji Wang,Virawudh Soontornniyomkij +9 more
TL;DR: HIV mediates a productive infection of brain macrophages/microglia and there was no evidence supporting the hypothesis of substantial neuronal or macroglial infection, or evidence of substantial proviral burden prior to the development of productive infection.
Journal ArticleDOI
Pediatric Emergency Department Visits Associated with Mental Health Conditions Before and During the COVID-19 Pandemic - United States, January 2019-January 2022.
Lakshmi Radhakrishnan,Rebecca T. Leeb,Rebecca H. Bitsko,Kelly Carey,Abigail Gates,Kristin M. Holland,Kathleen P. Hartnett,Aaron Kite-Powell,Jourdan DeVies,Amanda Smith,Katharina L. van Santen,Sophia Crossen,Michael Sheppard,Samantha Wotiz,Rashon I. Lane,Rashid Njai,Amelia G Johnson,Amber K Winn,Hannah L Kirking,Loren Rodgers,Craig W. Thomas,Karl Soetebier,Jennifer Adjemian,Kayla N. Anderson +23 more
TL;DR: CDC examined changes in U.S. pediatric ED visits for overall mental health conditions (MHCs) and ED visits associated with specific MHCs (depression; anxiety; disruptive behavioral and impulse-control disorders; attention-deficit/hyperactivity disorder; trauma and stressor-related disorders; bipolar disorders; eating disorders; tic disorders; and obsessive-compulsive disorders) during 2019 through January 2022.
Journal ArticleDOI
Pediatric Emergency Department Visits Before and During the COVID-19 Pandemic - United States, January 2019-January 2022.
Lakshmi Radhakrishnan,Kelly Carey,Kathleen P. Hartnett,Aaron Kite-Powell,Marissa L. Zwald,Kayla N. Anderson,Rebecca T. Leeb,Kristin M. Holland,Abigail Gates,Jourdan DeVies,Amanda Smith,Katharina L. van Santen,Sophia Crossen,Michael Sheppard,Samantha Wotiz,Amelia G Johnson,Amber K Winn,Hannah L Kirking,Rashon I. Lane,Rashid Njai,Loren Rodgers,Craig W. Thomas,Karl Soetebier,Jennifer Adjemian +23 more
TL;DR: Health care providers and families should remain vigilant for potential indirect impacts of the COVID-19 pandemic, including health conditions resulting from delayed care, and increasing emotional distress and behavioral health concerns among children and adolescents.
Journal ArticleDOI
Damage and repair of DNA in HIV encephalitis.
Clayton A. Wiley,Cristian L. Achim,Robert Hammond,Seth Love,Eliezer Masliah,Lakshmi Radhakrishnan,Virginia J. Sanders,Guoji Wang +7 more
TL;DR: In this paper, the authors examined the brains from 15 AIDS autopsies for the presence of DNA strand breaks, for associated changes in the expression of the DNA repair enzymes KU80 and Poly (ADP-ribose) polymerase (PARP), and for accumulation of amyloid precursor protein (APP).