L
Lama Kdouh
Researcher at Beckman Coulter
Publications - 3
Citations - 159
Lama Kdouh is an academic researcher from Beckman Coulter. The author has contributed to research in topics: Viremia & Inflammation. The author has an hindex of 2, co-authored 3 publications receiving 82 citations.
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Journal ArticleDOI
CCR5 Inhibition in Critical COVID-19 Patients Decreases Inflammatory Cytokines, Increases CD8 T-Cells, and Decreases SARS-CoV2 RNA in Plasma by Day 14.
Bruce K. Patterson,Harish Seethamraju,Kush Dhody,Michael J. Corley,Kazem Kazempour,Jay Lalezari,Alina P.S. Pang,Christopher Sugai,Eisa Mahyari,Edgar B. Francisco,Amruta Pise,Hallison Rodrigues,Helen L. Wu,Gabriela M. Webb,Byung Park,Scott Kelly,Nader Pourhassan,Alina Lelic,Lama Kdouh,Monica Herrera,Eric W. Hall,Benjamin N. Bimber,Matthew Plassmeyer,Raavi Gupta,Oral Alpan,Jane A. O’Halloran,Philip A. Mudd,Enver Akalin,Lishomwa C. Ndhlovu,Jonah B. Sacha +29 more
TL;DR: While the current study design precludes clinical efficacy inferences, these results implicate CCR5 as a therapeutic target for COVID-19 and form the basis for ongoing randomized clinical trials.
Posted ContentDOI
Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19
Bruce Pattterson,Harish Seetthamraju,Kush Dhody,Michael J. Corley,Kazem Kazempour,Jay Lalezari,Alina Pang,Christopher Sugai,Edgar B. Francisco,Amruta Pise,Hallison Rodrigues,Matthew Ryou,Helen L. Wu,Gabriela M. Webb,Byung Park,Scott Kelly,Nader Pourhassan,Alena Lelic,Lama Kdouh,Monica Herrera,Eric W. Hall,Enver Aklin,Lishomwa C. Ndhlovu,Jonah B. Sacha +23 more
TL;DR: A novel approach to resolving unchecked inflammation, restoring immunologic deficiencies, and reducing SARS-CoV-2 plasma viral load via disruption of the CCL5-CCR5 axis is demonstrated and support randomized clinical trials to assess clinical efficacy of leronlimab-mediated inhibition of CCR5 for COVID-19.
Journal ArticleDOI
ICCS Women in Cytometry—Impact 10 years later: A call to promote gender equity
Silvia T Bunting,Teri Oldaker,Julianne Qualtieri,Melanie O'Donahue,Sara Maremont,Heather Harricharran,Abigail S. Kelliher,Lama Kdouh,Katherine Devitt,Sindhu Cherian,Maryalice Stetler-Stevenson,Jonni S. Moore +11 more