L
Lan Yu
Researcher at University of California, Davis
Publications - 15
Citations - 2228
Lan Yu is an academic researcher from University of California, Davis. The author has contributed to research in topics: Galectin & Apoptosis. The author has an hindex of 13, co-authored 15 publications receiving 2068 citations. Previous affiliations of Lan Yu include La Jolla Institute for Allergy and Immunology.
Papers
More filters
Journal ArticleDOI
Human Galectin-3 Is a Novel Chemoattractant for Monocytes and Macrophages
Hideki Sano,Daniel K. Hsu,Lan Yu,John R. Apgar,Ichiro Kuwabara,Tohru Yamanaka,Mitsuomi Hirashima,Fu-Tong Liu +7 more
TL;DR: The results indicate that galectin-3 is a novel chemoattractant for monocytes and macrophages and suggest that the effect is mediated at least in part through a PTX-sensitive (G protein-coupled) pathway.
Journal ArticleDOI
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.
Daniel K. Hsu,Ri Yao Yang,Zhixing Pan,Lan Yu,Daniel R. Salomon,Wai-Ping Fung-Leung,Fu-Tong Liu +6 more
TL;DR: It was found that peritoneal macrophages from gal3(-/-) mice were more prone to undergo apoptosis than those from Gal3(+/+) mice when treated with apoptotic stimuli, suggesting that expression of galectin-3 in inflammatory cells may lead to longer cell survival, thus prolonging inflammation.
Journal ArticleDOI
Critical role of galectin-3 in phagocytosis by macrophages
Hideki Sano,Daniel K. Hsu,Daniel K. Hsu,John R. Apgar,Lan Yu,Lan Yu,Bhavya Bhavna Sharma,Ichiro Kuwabara,Ichiro Kuwabara,Shozo Izui,Fu-Tong Liu +10 more
TL;DR: Gal3-/- macrophages exhibited a lower degree of actin rearrangement upon Fcgamma receptor crosslinkage, indicating that galectin-3 contributes to macrophage phagocytosis through an intracellular mechanism.
Journal ArticleDOI
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma
Riaz I. Zuberi,Daniel K. Hsu,Omer Kalayci,Huan Yuan Chen,Holly K. Sheldon,Lan Yu,John R. Apgar,Toshiaki Kawakami,Craig M. Lilly,Fu-Tong Liu +9 more
TL;DR: It is concluded that galectin-3 may play an important role in the pathogenesis of asthma and inhibitors of this lectin may prove useful for treatment of this disease.
Journal ArticleDOI
Cell cycle regulation by galectin-12, a new member of the galectin superfamily.
TL;DR: It is concluded that galectin-12 is a novel regulator of cellular homeostasis, which contains two domains that are homologous to the galECTin CRD.