L
Lara Leoni
Researcher at University of Chicago
Publications - 24
Citations - 1510
Lara Leoni is an academic researcher from University of Chicago. The author has contributed to research in topics: Nanoporous & Islet. The author has an hindex of 14, co-authored 22 publications receiving 1431 citations. Previous affiliations of Lara Leoni include University of Illinois at Urbana–Champaign & University of Illinois at Chicago.
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Journal ArticleDOI
Influence of engineered titania nanotubular surfaces on bone cells.
TL;DR: In vivo biocompatibility results suggest that nanotubular titania does not cause chronic inflammation or fibrosis, and the fabrication routes of titania nano-architectures are flexible and cost-effective, enabling realization of desired platform topologies on existing non-planar orthopedic implants.
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Nanoporous anti-fouling silicon membranes for biosensor applications.
TL;DR: Results indicate that micromachined silicon membranes can be fabricated with uniform pore sizes capable of the simultaneous exclusion of albumin and diffusion of glucose, and point to the potential of using such membranes for implantable biosensor applications.
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Biocompatibility of nanoporous alumina membranes for immunoisolation
Kristen E La Flamme,Ketul C. Popat,Lara Leoni,Erica Markiewicz,Thomas J. La Tempa,Brian B. Roman,Craig A. Grimes,Tejal A. Desai,Tejal A. Desai +8 more
TL;DR: In vivo work has demonstrated that implantation of these capsules into the peritoneal cavity of rats induces a transient inflammatory response, and that PEG is useful in minimizing the host response to the material.
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Characterization of Nanoporous Membranes for Immunoisolation: Diffusion Properties and Tissue Effects
TL;DR: In this study, diffusion of biologically relevant molecules through the microfabricated membrane was characterized using a two-compartment diffusion chamber and, to improve in vivo long term diffusion performance, biocapsules were implanted in animals and the degree of foreign body response was assessed.
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Micromachined biocapsules for cell-based sensing and delivery
Lara Leoni,Tejal A. Desai +1 more
TL;DR: The creation of monodisperse, nanoporous, biocompatible, silicon membranes as a platform for the delivery of cells and the interaction of silicon-based substrates with cells of interest in terms of viability, proliferation, and functionality is described.