Larraitz Arriola

TL;DR: Results from this survey indicate that a possible common source of development of the disease does not seem to be the reason of the high sCJD incidence and the posterior relative risk distribution showed no excess risk areas.

TL;DR: There were no substantial differences between independent analyses of each subgroup and hierarchical models when using the EUROCAT anomaly subgroups, suggesting that considering each anomaly separately remains an appropriate method for the detection of potential changes in prevalence by surveillance systems.

TL;DR: This update to the EUROCAT antiepileptic-study dataset included 226,806 live births, stillbirths, or terminations with malformations among 7.6 million births in 20 European countries from 1995 to 2010, more than twice the population of the original study, and found no evidence of an increased risk of isolated orofacial clefts relative to other malformation for LTG monotherapy exposure in the first trimester.

TL;DR: HOS is a rare genetic condition showing regional variation in its prevalence and is often missed prenatally, in spite of the existence of major structural anomalies, which is important information for counselling purposes.