D
David Prieto-Merino
Researcher at University of London
Publications - 105
Citations - 7299
David Prieto-Merino is an academic researcher from University of London. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 31, co-authored 91 publications receiving 5663 citations. Previous affiliations of David Prieto-Merino include University of Murcia & University of Alcalá.
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Journal ArticleDOI
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
Ian Roberts,Haleema Shakur,AO Afolabi,Karim Brohi,Timothy J Coats,Yashbir Dewan,Satoshi Gando,Gordon H. Guyatt,Beverley J. Hunt,Carlos Morales,Pablo Perel,David Prieto-Merino,Tom Woolley +12 more
TL;DR: Strong evidence is recorded that tranexamic acid should be given as early as possible to bleeding trauma patients with significant haemorrhage, and for trauma patients admitted late after injury, tranExamic acid is less effective and could be harmful.
Journal ArticleDOI
The weight of nations: an estimation of adult human biomass
TL;DR: Increasing population fatness could have the same implications for world food energy demands as an extra half a billion people living on the earth.
Journal ArticleDOI
Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data
Michael V. Holmes,Michael V. Holmes,Caroline Dale,Luisa Zuccolo,Richard J. Silverwood,Yiran Guo,Zheng Ye,David Prieto-Merino,Abbas Dehghan,Stella Trompet,Andrew Wong,Alana Cavadino,Dagmar Drogan,Sandosh Padmanabhan,Shanshan Li,Ajay Yesupriya,Maarten Leusink,Johan Sundström,Jaroslav A. Hubacek,Hynek Pikhart,Daniel I. Swerdlow,Andrie G. Panayiotou,S. A. Borinskaya,Chris Finan,Sonia Shah,Karoline Kuchenbaecker,Tina Shah,Jorgen Engmann,Lasse Folkersen,Per Eriksson,Fulvio Ricceri,Olle Melander,Carlotta Sacerdote,Dale M Gamble,Sruti Rayaprolu,Owen A. Ross,Stela McLachlan,OV Vikhireva,Ivonne Sluijs,Robert A. Scott,Vera Adamkova,Leon Flicker,Frank M. van Bockxmeer,Christine Power,Pedro Marques-Vidal,Tom W. Meade,Michael Marmot,José M. Ferro,Sofia Paulos-Pinheiro,Steve E. Humphries,Philippa J. Talmud,Irene Mateo Leach,Niek Verweij,Allan Linneberg,Tea Skaaby,Pieter A. Doevendans,Maarten J Cramer,Pim van der Harst,Olaf H. Klungel,Nicole F. Dowling,Anna F. Dominiczak,Meena Kumari,Andrew N. Nicolaides,Cornelia Weikert,Heiner Boeing,Shah Ebrahim,Tom R. Gaunt,Jackie F. Price,Lars Lannfelt,Anne Peasey,Ruzena Kubinova,Andrzej Pajak,Sofia Malyutina,Mikhail Voevoda,Mikhail Voevoda,Abdonas Tamosiunas,Anke H. Maitland-van der Zee,Paul Norman,Graeme J. Hankey,Graeme J. Hankey,Manuela M. Bergmann,Albert Hofman,Oscar H. Franco,Jackie A. Cooper,Jutta Palmen,Wilko Spiering,Pim A. de Jong,Diana Kuh,Rebecca Hardy,André G. Uitterlinden,M. Arfan Ikram,Ian Ford,Elina Hyppönen,Elina Hyppönen,Osvaldo P. Almeida,Osvaldo P. Almeida,Nicholas J. Wareham,Kay-Tee Khaw,Anders Hamsten,Anders Hamsten,Lise Lotte N. Husemoen,Anne Tjønneland,Janne Schurmann Tolstrup,Eric B. Rimm,Eric B. Rimm,Joline W.J. Beulens,W. M. Monique Verschuren,N. Charlotte Onland-Moret,Marten H. Hofker,S. Goya Wannamethee,Peter H. Whincup,Richard W Morris,Astrid M. Vicente,Hugh Watkins,Hugh Watkins,Martin Farrall,Martin Farrall,J. Wouter Jukema,James F. Meschia,L. Adrienne Cupples,Stephen J. Sharp,Myriam Fornage,Charles Kooperberg,Andrea Z. LaCroix,James Y. Dai,Matthew B. Lanktree,David S. Siscovick,Eric Jorgenson,Bonnie Spring,Josef Coresh,Yun Li,Sarah G. Buxbaum,Pamela J. Schreiner,R. Curtis Ellison,Michael Y. Tsai,Sanjay R. Patel,Sanjay R. Patel,Susan Redline,Andrew D. Johnson,Ron C. Hoogeveen,Hakon Hakonarson,Jerome I. Rotter,Eric Boerwinkle,Paul I.W. de Bakker,Mika Kivimäki,Folkert W. Asselbergs,Folkert W. Asselbergs,Naveed Sattar,Debbie A Lawlor,John C. Whittaker,John C. Whittaker,George Davey Smith,Kenneth J. Mukamal,Bruce M. Psaty,Bruce M. Psaty,James G. Wilson,Leslie A. Lange,Ajna Hamidovic,Aroon D. Hingorani,Børge G. Nordestgaard,Børge G. Nordestgaard,Martin Bobak,David A. Leon,Claudia Langenberg,Tom Palmer,Alexander P. Reiner,Brendan J. Keating,Brendan J. Keating,Frank Dudbridge,Juan P. Casas,Juan P. Casas +170 more
TL;DR: In this article, the causal role of alcohol consumption in cardiovascular disease was investigated using a Mendelian randomisation meta-analysis of 56 epidemiological studies, including 20 259 coronary heart disease cases and 10 164 stroke events.
Journal ArticleDOI
Metabolite Profiling and Cardiovascular Event Risk A Prospective Study of 3 Population-Based Cohorts
Peter Würtz,Aki S. Havulinna,Pasi Soininen,Tuulia Tynkkynen,David Prieto-Merino,Therese Tillin,Anahita Ghorbani,Anna Artati,Qin Wang,Mika Tiainen,Antti J. Kangas,Johannes Kettunen,Jari Kaikkonen,Vera Mikkilä,Antti Jula,Mika Kähönen,Terho Lehtimäki,Debbie A Lawlor,Tom R. Gaunt,Alun D. Hughes,Naveed Sattar,Thomas Illig,Jerzy Adamski,Thomas J. Wang,Markus Perola,Samuli Ripatti,Ramachandran S. Vasan,Olli T. Raitakari,Robert E. Gerszten,Juan-Pablo Casas,Nish Chaturvedi,Mika Ala-Korpela,Veikko Salomaa +32 more
TL;DR: The value of high-throughput metabolomics for biomarker discovery and improved risk assessment is substantiated and the value of net reclassification was particularly improved for persons in the 5% to 10% risk range.
Journal ArticleDOI
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Ian Roberts,Haleema Shakur,Timothy J Coats,Beverley J. Hunt,Eni Balogun,L Barnetson,L Cook,T Kawahara,Pablo Perel,David Prieto-Merino,M Ramos,John Cairns,Carla Guerriero +12 more
TL;DR: The CRASH-2 trial aimed to determine the effect of the early administration of tranexamic acid on death and transfusion requirement in bleeding trauma patients and the cost-effectiveness of the short course of TXA on death, vascular occlusive events and the receipt of blood transfusion in trauma patients.