L
Lars Maßhöfer
Researcher at University of Duisburg-Essen
Publications - 3
Citations - 575
Lars Maßhöfer is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Exome & Methylated DNA immunoprecipitation. The author has an hindex of 2, co-authored 2 publications receiving 502 citations.
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Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3.
Marcel Martin,Marcel Martin,Lars Maßhöfer,Petra Temming,Sven Rahmann,Claudia H D Metz,Norbert Bornfeld,Johannes van de Nes,Ludger Klein-Hitpass,Alan G. Hinnebusch,Bernhard Horsthemke,Dietmar R. Lohmann,Michael Zeschnigk +12 more
TL;DR: Using exome sequencing, recurrent somatic mutations in EIF1AX and SF3B1 are identified occurring in uveal melanomas with disomy 3, which rarely metastasize and are associated with poor prognosis.
Journal ArticleDOI
A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): analysis of the retinoblastoma locus
Michael Zeschnigk,Stefan Böhringer,Elizabeth Price,Zerrin Onadim,Lars Maßhöfer,Dietmar R. Lohmann +5 more
TL;DR: This novel technical approach is used to identify hypermethylation of the CpG island located in the promoter region of the retinoblastoma (RB1) gene and found that QAMA facilitates reliable and fast measurement of the relative quantity of methylated alleles and improves handling of diagnostic methylation analysis.
Journal ArticleDOI
Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies
Jan Kehrmann,Anna Höwner,Lara Best,Lars Maßhöfer,Michael Zeschnigk,Jürgen C. Becker,Dirk Schadendorf,Jan Buer,Alexander Roesch +8 more
TL;DR: In this article , the lesion-directed treatments for actinic keratosis (AK), its progression into squamous skin cancer, and for field-directed treatment response is not established.