L
Laura Corbo
Researcher at University of Lyon
Publications - 48
Citations - 2801
Laura Corbo is an academic researcher from University of Lyon. The author has contributed to research in topics: Estrogen receptor alpha & Estrogen receptor. The author has an hindex of 26, co-authored 47 publications receiving 2558 citations. Previous affiliations of Laura Corbo include Centre national de la recherche scientifique & Claude Bernard University Lyon 1.
Papers
More filters
Journal ArticleDOI
Cracking the Estrogen Receptor's Posttranslational Code in Breast Tumors
Muriel Le Romancer,Coralie Poulard,Pascale A. Cohen,Stéphanie Sentis,Jack-Michel Renoir,Jack-Michel Renoir,Laura Corbo +6 more
TL;DR: A thorough understanding of the complete picture of these modifications in ER carcinogenesis might not only open new avenues for identifying new markers for prognosis or prediction of response to endocrine therapy but also could promote the development of novel therapeutic strategies.
Journal ArticleDOI
Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1
Muriel Le Romancer,Muriel Le Romancer,Isabelle Treilleux,Isabelle Treilleux,Nicolas Leconte,Nicolas Leconte,Yannis Robin-Lespinasse,Yannis Robin-Lespinasse,Stéphanie Sentis,Stéphanie Sentis,Katia Bouchekioua-Bouzaghou,Katia Bouchekioua-Bouzaghou,Sophie Goddard,Stéphanie Gobert-Gosse,Laura Corbo,Laura Corbo +15 more
TL;DR: The data indicate that the methylation of ERalpha is a physiological process occurring in the cytoplasm of normal and malignant epithelial breast cells and that ER alpha is hypermethylated in a subset of breast cancers.
Journal ArticleDOI
Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.
TL;DR: It is demonstrated that ERα is sumoylated at conserved lysine residues within the hinge region, and SUMO-1 appears to regulate ERα-dependent transcription.
Journal ArticleDOI
The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation.
Déborah Prévôt,Thibault Voeltzel,Anne-Marie Birot,Anne-Pierre Morel,Marie-Claude Rostan,Jean-Pierre Magaud,Laura Corbo +6 more
TL;DR: The data indicate that Btg1 and Btg2 act as transcriptional cofactors of the Hoxb9 protein, and suggest that this interaction may mediate their antiproliferative function.
Journal ArticleDOI
Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding.
Anne Dupressoir,Anne-Pierre Morel,Willy Barbot,Marie-Paule Loireau,Laura Corbo,Thierry Heidmann +5 more
TL;DR: The mammalian orthologs of yCCR4 are identified and it is shown that the human member binds to the human yPOP2 homologs, thus strongly suggesting conservation of the CCR4-NOT complex from yeast to human.