Laura de Girolamo

TL;DR: Recent developments regarding MSCs properties, physiological effects, delivery, clinical applications and possible side effects are described.

TL;DR: It is shown that age does not seem to affect cell viability and in vitro adipocytic differentiation significantly, whereas it does affects osteoblastic differentiation, in the absence and presence of two-dimensional and three-dimensional scaffolds.

TL;DR: Analysis and characterized adipose-derived stem cells isolated from adipose tissue of rat, rabbit and pig and compared their in vitro osteogenic differentiation abilities for exploitation in the repair of critical osteochondral defects in autologous pre-clinical models.

TL;DR: Despite the constant presence of positive and satisfactory results in the studies analyzed, the complexity of MSC metabolism and related therapeutic effects do not allow withdrawing definitive conclusions about the superiority of one tissue source over another, as well as about the best cell dose and the long-term durability of the effects of these procedures.

TL;DR: Both PRP and SVF were safe, effective treatments for recalcitrant Achilles tendinopathy, and the patients treated with SVF obtained faster results, thus suggesting that such a treatment should be taken into consideration for those patients who require an earlier return to daily activities or sport.