M
Marco Viganò
Researcher at University of Milan
Publications - 94
Citations - 1457
Marco Viganò is an academic researcher from University of Milan. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 18, co-authored 73 publications receiving 876 citations. Previous affiliations of Marco Viganò include University of Milano-Bicocca & Yeshiva University.
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Journal ArticleDOI
Intratendinous adipose-derived stromal vascular fraction (SVF) injection provides a safe, efficacious treatment for Achilles tendinopathy: results of a randomized controlled clinical trial at a 6-month follow-up
Federico Giuseppe Usuelli,Miriam Grassi,Camilla Maccario,Marco Viganò,L Lanfranchi,Umberto Alfieri Montrasio,Laura de Girolamo +6 more
TL;DR: Both PRP and SVF were safe, effective treatments for recalcitrant Achilles tendinopathy, and the patients treated with SVF obtained faster results, thus suggesting that such a treatment should be taken into consideration for those patients who require an earlier return to daily activities or sport.
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Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease
Enrico Ragni,Carlotta Perucca Orfei,Paola De Luca,Carlotta Mondadori,Marco Viganò,Alessandra Colombini,Laura de Girolamo +6 more
TL;DR: To deeply characterize adipose-derived MSC (ASC)-secreted factors and EV-miRNAs, and their modulation after IFNγ preconditioning, ASC secretome showed a marked capacity to stimulate cell motility and modulate inflammatory and degenerative processes.
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Low frequency pulsed electromagnetic field affects proliferation, tissue-specific gene expression, and cytokines release of human tendon cells.
L. de Girolamo,D. Stanco,Emanuela Galliera,Marco Viganò,Alessandra Colombini,Stefania Setti,Elena Vianello,M.M. Corsi Romanelli,Valerio Sansone +8 more
TL;DR: It is demonstrated that PEMF positively influence, in a dose-dependent manner, the proliferation, tendon-specific marker expression, and release of anti-inflammatory cytokines and angiogenic factor in a healthy human TCs culture model.
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Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes
Enrico Ragni,Carlotta Perucca Orfei,Paola De Luca,Gaia Lugano,Marco Viganò,Alessandra Colombini,Federico Valli,Daniele Zacchetti,Valentina Bollati,Laura de Girolamo +9 more
TL;DR: ASC-EVs confirm their role as a novel therapeutic option for osteoarthritic joints through direct interaction with HA matrix and miRNA release andBioinformatics analysis of EV-embedded miRNAs showed their ability to potentially regulate the main pathways strictly associated with synovial inflammation in OA.
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Mesenchymal stem cells in the treatment of articular cartilage degeneration: New biological insights for an old-timer cell.
Alessandra Colombini,Carlotta Perucca Orfei,Dimitrios Kouroupis,Enrico Ragni,Paola De Luca,Marco Viganò,Diego Correa,Laura de Girolamo +7 more
TL;DR: This review focuses on the two aspects of the use of MSCs for articular cartilage damage, namely, cell therapy and tissue engineering, providing information on their use criteria, advancements, challenges and strategies to overcome them.