L
Laura Leccesi
Researcher at Catholic University of the Sacred Heart
Publications - 8
Citations - 2088
Laura Leccesi is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 8, co-authored 8 publications receiving 1910 citations.
Papers
More filters
Journal ArticleDOI
Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes
Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Amerigo Iaconelli,Laura Leccesi,Giuseppe Nanni,Alfons Pomp,Marco Castagneto,Giovanni Ghirlanda,Francesco Rubino +10 more
TL;DR: In severely obese patients with type 2 diabetes, bariatric surgery resulted in better glucose control than did medical therapy and preoperative BMI and weight loss did not predict the improvement in hyperglycemia after these procedures.
Journal ArticleDOI
Bariatric Surgery Versus Conventional Medical Therapy for Type 2 Diabetes
Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Amerigo Iaconelli,Laura Leccesi,Giuseppe Nanni,Alfons Pomp,Marco Castagneto,Giovanni Ghirlanda,Francesco Rubino +10 more
TL;DR: The investigators concluded that bariatric surgery is a potentially beneficial intervention for management of uncontrolled diabetes because it eliminated the need for diabetic medications in some patients and impressively reduced theneed for drug therapy in others.
Journal ArticleDOI
Influence of maternal obesity on insulin sensitivity and secretion in offspring.
Geltrude Mingrone,Melania Manco,Maria Elena Valera Mora,Caterina Guidone,Amerigo Iaconelli,Donatella Gniuli,Laura Leccesi,Chiara Chiellini,Giovanni Ghirlanda +8 more
TL;DR: The maternal genetic/epigenetic transmission shows a clear sexual dimorphism, with male offspring having a higher value of insulin sensitivity (although not statistically significant) associated with significantly higher insulin secretion than female offspring.
Journal ArticleDOI
Effects of Bilio-Pancreatic Diversion on Diabetic Complications: A 10-year follow-up
Amerigo Iaconelli,Simona Panunzi,Andrea De Gaetano,Melania Manco,Caterina Guidone,Laura Leccesi,Donatella Gniuli,Giuseppe Nanni,Marco Castagneto,Giovanni Ghirlanda,Geltrude Mingrone +10 more
TL;DR: Renal and cardiovascular complications were dramatically reduced in the surgical arm, indicating long-term benefits of BPD on diabetic complications, at least in the case of morbid obesity with decompensated type 2 diabetes.
Journal ArticleDOI
Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion
Geltrude Mingrone,Giuseppe Nolfe,G. Castagneto Gissey,Antonio Iaconelli,Laura Leccesi,Caterina Guidone,Giuseppe Nanni,Jens J. Holst +7 more
TL;DR: An incretin circadian rhythm was shown for the first time in morbid obesity and could not be overcome by surgery in diabetes, suggesting a role in insulin resistance and diabetes.