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Laura Leccesi

Researcher at Catholic University of the Sacred Heart

Publications -  8
Citations -  2088

Laura Leccesi is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 8, co-authored 8 publications receiving 1910 citations.

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Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes

TL;DR: In severely obese patients with type 2 diabetes, bariatric surgery resulted in better glucose control than did medical therapy and preoperative BMI and weight loss did not predict the improvement in hyperglycemia after these procedures.
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Bariatric Surgery Versus Conventional Medical Therapy for Type 2 Diabetes

TL;DR: The investigators concluded that bariatric surgery is a potentially beneficial intervention for management of uncontrolled diabetes because it eliminated the need for diabetic medications in some patients and impressively reduced theneed for drug therapy in others.
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Influence of maternal obesity on insulin sensitivity and secretion in offspring.

TL;DR: The maternal genetic/epigenetic transmission shows a clear sexual dimorphism, with male offspring having a higher value of insulin sensitivity (although not statistically significant) associated with significantly higher insulin secretion than female offspring.
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Effects of Bilio-Pancreatic Diversion on Diabetic Complications: A 10-year follow-up

TL;DR: Renal and cardiovascular complications were dramatically reduced in the surgical arm, indicating long-term benefits of BPD on diabetic complications, at least in the case of morbid obesity with decompensated type 2 diabetes.
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Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion

TL;DR: An incretin circadian rhythm was shown for the first time in morbid obesity and could not be overcome by surgery in diabetes, suggesting a role in insulin resistance and diabetes.