L
Laura Zambonin
Researcher at University of Bologna
Publications - 35
Citations - 1956
Laura Zambonin is an academic researcher from University of Bologna. The author has contributed to research in topics: Glucose transporter & Glucose uptake. The author has an hindex of 23, co-authored 34 publications receiving 1807 citations.
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Journal ArticleDOI
Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway
Annalisa Lonetti,Alessandra Cappellini,Alice Bertaina,Franco Locatelli,Andrea Pession,Francesca Buontempo,Camilla Evangelisti,Cecilia Evangelisti,Ester Orsini,Laura Zambonin,Luca M. Neri,Alberto M. Martelli,Francesca Chiarini +12 more
TL;DR: Findings indicate that nelarabine in combination with PI3K inhibitors may be a promising therapeutic strategy for the treatment of T-ALL relapsed patients.
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Nox-generated ROS modulate glucose uptake in a leukaemic cell line.
TL;DR: By treating an acute leukaemic cell line with different antioxidants, ROS generation was shown to be crucially involved in the modulation of glucose transport (mediated by Glut1), which is frequently up-regulated in cancer cells, and data suggest that both Glut 1 and Nox homologues may be considered new potential targets in the treatment of leukaemia.
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Polyphenols as Modulators of Aquaporin Family in Health and Disease.
TL;DR: This review offers an overview about the role of AQPs in brain, eye, skin diseases, and metabolic syndrome, focusing on the ability of polyphenols to modulate AQP expression.
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Induction of apoptosis in a human leukemic cell line via reactive oxygen species modulation by antioxidants
TL;DR: Results show that ROS production induced by IL-3 can protect leukemic cells from apoptosis, the effect being counteracted by antioxidants.
Journal ArticleDOI
Contribution of reactive oxygen species to the regulation of Glut1 in two hemopoietic cell lines differing in cytokine sensitivity.
Diana Fiorentini,Cecilia Prata,Tullia Maraldi,Laura Zambonin,Laura Bonsi,Gabriele Hakim,Laura Landi +6 more
TL;DR: Differences in acute regulation of glucose transport activity in the two cell lines may be related to differences in amplitude and spatial organization of ROS production.