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Laurel J. Gabard-Durnam
Researcher at Boston Children's Hospital
Publications - 53
Citations - 3284
Laurel J. Gabard-Durnam is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Autism & Prefrontal cortex. The author has an hindex of 18, co-authored 44 publications receiving 2318 citations. Previous affiliations of Laurel J. Gabard-Durnam include Northeastern University & Harvard University.
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Journal ArticleDOI
Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation.
Dylan G. Gee,Laurel J. Gabard-Durnam,Jessica Flannery,Bonnie Goff,Kathryn L. Humphreys,Eva H. Telzer,Todd A. Hare,Susan Y. Bookheimer,Nim Tottenham +8 more
TL;DR: It is demonstrated that, as in the rodent, children who experienced early maternal deprivation exhibit early emergence of mature amygdala–prefrontal connectivity, suggesting that accelerated amygdala–mPFC development is an ontogenetic adaptation in response to early adversity.
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The Development of Human Amygdala Functional Connectivity at Rest from 4 to 23 Years: a cross-sectional study
Laurel J. Gabard-Durnam,Jessica Flannery,Bonnie Goff,Dylan G. Gee,Kathryn L. Humphreys,Eva H. Telzer,Todd A. Hare,Nim Tottenham +7 more
TL;DR: There are extensive changes in amygdala-cortical functional connectivity that emerge between childhood and adolescence, and particularly robust convergence of FC for all subregions with the mPFC.
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Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence
Dylan G. Gee,Laurel J. Gabard-Durnam,Eva H. Telzer,Kathryn L. Humphreys,Bonnie Goff,Mor Shapiro,Jessica Flannery,Daniel S. Lumian,Dominic S. Fareri,Christina Caldera,Nim Tottenham +10 more
TL;DR: Maternal buffering in childhood, but not adolescence, suggests that childhood may be a sensitive period for amygdala-prefrontal development and suggests a neural mechanism through which caregivers modulate children’s regulatory behavior by inducing more mature connectivity and buffering against heightened reactivity.
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The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data
TL;DR: The Harvard Automated Processing Pipeline for EEG (HAPPE) is proposed as a standardized, automated pipeline compatible with EEG recordings of variable lengths and artifact contamination levels, including high-artifact and short EEG recordings from young children or those with neurodevelopmental disorders.
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Early Adversity and Critical Periods: Neurodevelopmental Consequences of Violating the Expectable Environment
TL;DR: The various ways adversity becomes neurobiologically embedded are discussed, and how the timing of such adversity plays an important role in determining outcomes are offered.