L
Laurence Vergne
Researcher at Institut de recherche pour le développement
Publications - 27
Citations - 2339
Laurence Vergne is an academic researcher from Institut de recherche pour le développement. The author has contributed to research in topics: Viral load & Drug resistance. The author has an hindex of 23, co-authored 27 publications receiving 2317 citations. Previous affiliations of Laurence Vergne include University of Montpellier.
Papers
More filters
Journal ArticleDOI
Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus.
Nicolas Nagot,Abdoulaye Ouedraogo,Vincent Foulongne,Issouf Konate,Helen A. Weiss,Laurence Vergne,Marie-Christine Defer,Didier Djagbaré,A. Sanon,Jean-Baptiste Andonaba,Pierre Becquart,Michel Segondy,Roselyne Vallo,Adrien Sawadogo,Philippe Van de Perre,Philippe Mayaud +15 more
TL;DR: HSV suppressive therapy significantly reduces genital and plasma HIV-1 RNA levels in dually infected women and may have important implications for HIV control.
Journal ArticleDOI
The Senegalese government's highly active antiretroviral therapy initiative: an 18-month follow-up study.
Christian Laurent,Ndella Diakhaté,Ndeye Fatou Ngom Gueye,Mame Awa Touré,Papa Salif Sow,Mame Awa Faye,Mandoumbé Gueye,Isabelle Lanièce,Coumba Toure Kane,Florian Liegeois,Laurence Vergne,Souleymane Mboup,Salif Badiane,Ibrahima Ndoye,Eric Delaporte +14 more
TL;DR: Clinical and biological results were comparable to those seen in western cohorts, despite differences in the HIV-1 subtype distribution and an advanced disease stage when the treatment was initiated, and shows that HAART is feasible and well tolerated in African patients.
Journal ArticleDOI
Genetic Diversity of Protease and Reverse Transcriptase Sequences in Non-Subtype-B Human Immunodeficiency Virus Type 1 Strains: Evidence of Many Minor Drug Resistance Mutations in Treatment-Naive Patients
Laurence Vergne,Martine Peeters,Eitel Mpoudi-Ngole,Anke Bourgeois,Florian Liegeois,Coumba Toure-Kane,Souleymane Mboup,Claire Mulanga-Kabeya,Eric Saman,Jacques Jourdan,Jacques Reynes,Eric Delaporte +11 more
TL;DR: Phenotypic and clinical studies are now required to determine whether multidrug-resistant viruses emerge more rapidly during antiretroviral therapy when minor resistance-conferring mutations are present before treatment initiation.
Journal ArticleDOI
Long-term benefits of highly active antiretroviral therapy in Senegalese HIV-1-infected adults.
Christian Laurent,Ndeye Fatou Ngom Gueye,Cheikh Tidiane Ndour,Pape Mandoumbé Gueye,Martin Diouf,Ndella Diakhaté,Ndeye Coumba Toure Kane,Isabelle Lanièce,Adama Ndir,Laurence Vergne,Ibrahima Ndoye,Souleymane Mboup,P.S. Sow,Eric Delaporte,Anrs +14 more
TL;DR: This study shows that clinical and biologic results similar to those seen in Western countries can be achieved and sustained during the long term in Africa.
Journal ArticleDOI
Characterization of a Highly Replicative Intergroup M/O Human Immunodeficiency Virus Type 1 Recombinant Isolated from a Cameroonian Patient
Martine Peeters,Florian Liegeois,Ndongo Torimiro,Anke Bourgeois,Eitel N. Mpoudi,Laurence Vergne,Eric Saman,Eric Delaporte,Sentob Saragosti +8 more
TL;DR: For the first time a recombination event in vivo between viruses belonging to two different groups, leading to a replicative virus is described, which will have important implications for diagnosis of HIV-1 infections by serological and molecular tests, as well as for antiviral treatment.