L
Laurent Fagni
Researcher at Centre national de la recherche scientifique
Publications - 2
Citations - 136
Laurent Fagni is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Metabotropic glutamate receptor 2 & Metabotropic receptor. The author has an hindex of 2, co-authored 2 publications receiving 134 citations. Previous affiliations of Laurent Fagni include Paris Descartes University.
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Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate between Metabotropic Glutamate Receptor Subtypes
TL;DR: Results demonstrate that the addition of a third carboxylic group to ACPD can change its activity (from agonist to antagonist) and either increase or decrease its selectivity and/or affinity for the various mGluR subtypes.
Journal ArticleDOI
Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate Between Metabotropic Glutamate Receptor Subtypes.
TL;DR: In this article, the four stereoisomers of 1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I, II, III) were synthesized and evaluated for their effects at glutamate receptors subtypes.