L
Le-Ping Yan
Researcher at Sun Yat-sen University
Publications - 29
Citations - 1371
Le-Ping Yan is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Fibroin & Self-healing hydrogels. The author has an hindex of 12, co-authored 26 publications receiving 1202 citations. Previous affiliations of Le-Ping Yan include Royal College of Surgeons in Ireland & University of Sydney.
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Journal ArticleDOI
Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications
Le-Ping Yan,Le-Ping Yan,Yingjun Wang,Li Ren,Gang Wu,Sofia G. Caridade,Jiabing Fan,Lingyun Wang,Ji Peihong,Joaquim M. Oliveira,João T. Oliveira,João F. Mano,Rui L. Reis +12 more
TL;DR: The results suggest that the genipin-cross-linked collagen/chitosan matrix may be a promising formulation for articular cartilage scaffolding.
Journal ArticleDOI
Macro/microporous silk fibroin scaffolds with potential for articular cartilage and meniscus tissue engineering applications.
Le-Ping Yan,Joaquim M. Oliveira,Ana Oliveira,Ana Oliveira,Sofia G. Caridade,João F. Mano,Rui L. Reis +6 more
TL;DR: The scaffolds developed in this study are proposed to be suitable for use in meniscus and cartilage tissue-engineered scaffolding as their structure integrity, morphology and mechanical properties were maintained after in vitro degradation for 30 days.
Journal ArticleDOI
Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells
Cristina Correia,Sarindr Bhumiratana,Le-Ping Yan,Ana Oliveira,Jeffrey M. Gimble,Danielle N. Rockwood,David L. Kaplan,Rui A. Sousa,Rui L. Reis,Gordana Vunjak-Novakovic +9 more
TL;DR: It is observed that 400-600 μm porous HFIP-derived silk fibroin scaffold demonstrated the best bone tissue formation outcomes, as evidenced by increased bone protein production, enhanced calcium deposition and total bone volume.
Journal ArticleDOI
Bilayered silk/silk-nanoCaP scaffolds for osteochondral tissue engineering: In vitro and in vivo assessment of biological performance.
Le-Ping Yan,Joana Silva-Correia,Mariana B. Oliveira,Carlos Vilela,Hélder Pereira,Rui A. Sousa,João F. Mano,Ana Oliveira,Joaquim M. Oliveira,Rui L. Reis +9 more
TL;DR: Novel porous bilayered scaffolds, fully integrating a silk fibroin layer and a silk-nano calcium phosphate layer for osteochondral defect (OCD) regeneration, were developed and showed that collagen II positive cartilage and glycosaminoglycan regeneration presented in the silk layer, and de novo bone ingrowths and vessel formation were observed in the Silk- nanoCaP layer.
Journal ArticleDOI
Tropoelastin Implants That Accelerate Wound Repair
Suzanne M. Mithieux,Behnaz Aghaei-Ghareh-Bolagh,Le-Ping Yan,Kekini V. Kuppan,Kekini V. Kuppan,Yiwei Wang,Francia Garces-Suarez,Zhe Li,Peter K.M. Maitz,Elizabeth A. Carter,Christina Limantoro,Wojciech Chrzanowski,David Cookson,Alan Riboldi-Tunnicliffe,Clair Baldock,Kosuke Ohgo,Kristin K. Kumashiro,Glenn A. Edwards,Anthony S. Weiss +18 more
TL;DR: A novel, pure, synthetic material is presented that promotes the repair of full‐thickness skin wounds using a novel heat‐based, stabilized form of human tropoelastin which allows for tunable resorption.