L
Lea Vacca Michel
Researcher at University of Rochester
Publications - 44
Citations - 625
Lea Vacca Michel is an academic researcher from University of Rochester. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 10, co-authored 22 publications receiving 563 citations. Previous affiliations of Lea Vacca Michel include Rochester General Health System & Rochester Institute of Technology.
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Journal ArticleDOI
VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients
Jon E. Peterson,David Zurakowski,Joseph E. Italiano,Joseph E. Italiano,Lea Vacca Michel,Lea Vacca Michel,Susan L. Connors,Oenick Marsha Denise Bale,Robert J. D'Amato,Giannoula Klement,Judah Folkman +10 more
TL;DR: Platelets sequester angiogenesis regulatory proteins which suggests an avenue for developing biomarkers to monitor disease and Multivariable logistic regression analysis indicated that PDGF, PF4 and VEGF were independent predictors of colorectal carcinoma and as a set provided statistically significant discrimination.
Journal ArticleDOI
Normal ranges of angiogenesis regulatory proteins in human platelets
Jon E. Peterson,David Zurakowski,Joseph E. Italiano,Joseph E. Italiano,Lea Vacca Michel,Lea Vacca Michel,Lucius Fox,Giannoula Klement,Judah Folkman +8 more
TL;DR: In this article, the platelet levels in isolated samples were determined utilizing a new actin ELISA method, which was used for accurate and reproducible measurement of vascular endothelial growth factor (VEGF), platelet derived growth factor, platelet factor 4 (PF4), thrombospondin-1 (TSP-1), fibroblast growth factors, basic (bFGF), and endostatin in platelets.
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A survey of educational uses of molecular visualization freeware
TL;DR: A survey to begin a systematic evaluation of the current classroom usage of molecular visualization found that the majority of respondents had used molecular visualization for more than 5 years and mentioned 32 different visualization tools used, with Jmol and PyMOL clearly standing out as the most frequently used programs at the present time.
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Heme Attachment Motif Mobility Tunes Cytochrome c Redox Potential
Lea Vacca Michel,Tao Ye,Sarah E. J. Bowman,Benjamin D. Levin,Megan A. Hahn,Brandy S. Russell,Sean Elliott,Kara L. Bren +7 more
TL;DR: The mobility of the CXXCH pentapeptide is found to impact the His-Fe(III) interaction and therefore the heme redox potential of Pseudomonas aeruginosa and Hydrogenobacter thermophilus.
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Haemophilus influenzae vaccine candidate outer membrane protein P6 is not conserved in all strains.
TL;DR: Results show that NTHi omp P6 is not invariant in its structure among respiratory isolates from children.