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Lee S-F Wu

Researcher at Johns Hopkins University

Publications -  4
Citations -  178

Lee S-F Wu is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Pregnancy & Infant mortality. The author has an hindex of 3, co-authored 4 publications receiving 134 citations.

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Modifiers of the effect of maternal multiple micronutrient supplementation on stillbirth, birth outcomes, and infant mortality: a meta-analysis of individual patient data from 17 randomised trials in low-income and middle-income countries

TL;DR: Antenatal multiple micronutrient supplements improved survival for female neonates and provided greater birth-outcome benefits for infants born to undernourished and anaemic pregnant women.
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The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children

TL;DR: Associations of anthropometric indicators of height, musculature, and fat mass with plasma proteins by using proteomics confirmed known biomarkers of childhood growth and revealed novel proteins associated with lean mass in chronically undernourished children.
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Circulating IGF-1 may mediate improvements in haemoglobin associated with vitamin A status during pregnancy in rural Nepalese women.

TL;DR: Examining the relationship between serum retinol, IGF-1, and Hb among pregnant women in extant samples collected during a placebo-controlled trial of VA and beta-carotene (BC) supplementation in rural Nepal concluded that increasing IGF- 1 was likely one mechanism by which Retinol improved circulating Hb in pregnant women of rural Nepal, although IGF-2 worked primarily through pathways independent of improved iron status indicators.
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Circulating Insulin-like Growth Factor-1 (IGF-1) is Associated with Vitamin A (VA) Status and Increased Circulating Hemoglobin (Hb) During Pregnancy in Nepalese Women

TL;DR: Erythropoiesis is compromised by vitamin A (VA) deficiency, and VA acts on the growth hormone/IGF-1 axis, and whether VA works through IGF-1 to enhance erythropOiesis in pregnancy has not been explored.