L
Lei Duan
Publications - 5
Citations - 287
Lei Duan is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 227 citations.
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Journal ArticleDOI
Safety and immunogenicity of a recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in Sierra Leone: a single-centre, randomised, double-blind, placebo-controlled, phase 2 trial
Fengcai Zhu,Alie H Wurie,Li-Hua Hou,Qi Liang,Yu-Hua Li,James B W Russell,Shipo Wu,Jingxin Li,Yuemei Hu,Guo Qiang,Wenbo Xu,Abdul R Wurie,Wen-Juan Wang,Zhe Zhang,Wen-Jiao Yin,Manal Ghazzawi,Xu Zhang,Lei Duan,Junzhi Wang,Wei Chen +19 more
TL;DR: The recombinant adenovirus type-5 vector-based Ebola vaccine was safe and highly immunogenic in healthy Sierra Leonean adults, and 8·0 × 1010 viral particles was the optimal dose.
Journal ArticleDOI
Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trial
Fengcai Zhu,Li-Hua Hou,Jingxin Li,Shipo Wu,Pei Liu,Gui-Rong Zhang,Yuemei Hu,Fan-Yue Meng,Junjie Xu,Rong Tang,Jie Zhang,Wen-Juan Wang,Lei Duan,Kai Chu,Qi Liang,Jialei Hu,Li Luo,Tao Zhu,Junzhi Wang,Wei Chen +19 more
TL;DR: The findings show that the high-dose vaccine is safe and robustly immunogenic and could mount glycoprotein-specific humoral and T-cell response against Ebola virus in 14 days.
Journal ArticleDOI
Development of a rapid and accurate CRISPR/Cas13-based diagnostic test for GII.4 norovirus infection
Lei Duan,Xiaohan Yang,Wenli Zhan,Yuan Tang,Mengru Wei,Keyi Chen,Pan Liu,Jia Xie,Changbin Zhang,Hongyu Zhao,Mingyong Luo +10 more
TL;DR: GII.4-CRISPR detection improves upon the shortcomings of some previously established molecular methods of detection, particularly with regard to accessibility and provides an alternative tool for outbreak control and early diagnosis of G II.4 norovirus infection.
Journal ArticleDOI
Enterovirus B types cause severe infection in infants aged 0–3 months
TL;DR: Wang et al. as mentioned in this paper conducted a retrospective study on hospitalized children with laboratory-confirmed EV infection (50 infants aged 0-3 months and 65 older than 3 months) at a tertiary care center in China.
Journal ArticleDOI
Genetic and clinical characteristics of genital Chlamydia trachomatis infection in Guangzhou, China.
Yuan Tang,Xiaohan Yang,Lei Duan,Wenli Zhan,Keyi Chen,Hui-Ying Chai,Pan Liu,Minchai Chen,Hongyu Zhao,Lihua Liang,Mengru Wei,Mingyong Luo +11 more
TL;DR: Wang et al. as discussed by the authors analyzed the genetic and clinical characteristics of genital CT infection among women in Guangzhou, China, from September 2020 to August 2021, a total of 8955 female patients were enrolled in this study.