L
Lei Wang
Researcher at Dalian Medical University
Publications - 4
Citations - 90
Lei Wang is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Liver injury & CYP8B1. The author has an hindex of 4, co-authored 4 publications receiving 65 citations.
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Journal ArticleDOI
A fully integrated and automated microsystem for rapid pharmacogenetic typing of multiple warfarin-related single-nucleotide polymorphisms.
Bin Zhuang,Junping Han,Guangxin Xiang,Wupeng Gan,Shuaiqin Wang,Dong Wang,Lei Wang,Jing Sun,Cai-Xia Li,Peng Liu +9 more
TL;DR: The successful development and operation of this microsystem establish the feasibility of rapid warfarin pharmacogenetic testing in routine clinical practice.
Journal ArticleDOI
Modulation of transport and metabolism of bile acids and bilirubin by chlorogenic acid against hepatotoxicity and cholestasis in bile duct ligation rats: involvement of SIRT1-mediated deacetylation of FXR and PGC-1α.
Li-li Zhu,Lei Wang,Fei Cao,Peng Liu,Haidong Bao,Yumei Yan,Xin Dong,Dong Wang,Zhongyu Wang,Peng Gong +9 more
TL;DR: The purpose of the present study was to investigate the effect and potential mechanism of chlorogenic acid on liver injury induced by cholestasis in a rat model of bile duct ligation (BDL).
Journal ArticleDOI
Andrographolide impairs alpha-naphthylisothiocyanate-induced cholestatic liver injury in vivo
Lei Wang,Fei Cao,Li-li Zhu,Peng Liu,Yuru Shang,Wen-hui Liu,Xin Dong,Haidong Bao,Peng Gong,Zhongyu Wang +9 more
TL;DR: The data suggest that andrographolide may impair cholestatic liver injury via anti-inflammatory and anti-oxidative stress.
Journal ArticleDOI
An automated microfluidic system for single-stranded DNA preparation and magnetic bead-based microarray analysis
Shuaiqin Wang,Yujia Sun,Wupeng Gan,Liu Yan,Guangxin Xiang,Dong Wang,Lei Wang,Jing Cheng,Peng Liu +8 more
TL;DR: The fully automated, "amplicon-in-answer-out" operation, together with the white-light detection, makes this integrated microfluidic device an excellent platform for low-cost, rapid genotyping in clinical diagnosis.