P
Peng Liu
Researcher at Tsinghua University
Publications - 229
Citations - 7405
Peng Liu is an academic researcher from Tsinghua University. The author has contributed to research in topics: Capillary electrophoresis & Gene. The author has an hindex of 35, co-authored 227 publications receiving 6245 citations. Previous affiliations of Peng Liu include Laboratory of Molecular Biology & Gladstone Institutes.
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Journal ArticleDOI
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
Yu-Fei He,Bin-Zhong Li,Zheng Li,Peng Liu,Yang Wang,Qingyu Tang,Jianping Ding,Yingying Jia,Zhangcheng Chen,Lin Li,Yan Sun,Xiuxue Li,Qing Dai,Chun-Xiao Song,Kangling Zhang,Chuan He,Guoliang Xu +16 more
TL;DR: It is demonstrated that 5mC and 5hmC in DNA are oxidized to 5-carboxylcytosine (5caC) by Tet dioxygenases in vitro and in cultured cells, suggesting that oxidation of 5m C by Tet proteins followed by TDG-mediated base excision of 5caC constitutes a pathway for active DNA demethylation.
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Receptor‐like kinase OsSIK1 improves drought and salt stress tolerance in rice (Oryza sativa) plants
Shouqiang Ouyang,Yunfeng Liu,Peng Liu,Gang Lei,He Sijie,Biao Ma,Wan-Ke Zhang,Jin-Song Zhang,Shou-Yi Chen +8 more
TL;DR: Results indicate that OsSIK1 plays important roles in salt and drought stress tolerance in rice, through the activation of the antioxidative system.
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Integrated portable polymerase chain reaction-capillary electrophoresis microsystem for rapid forensic short tandem repeat typing.
TL;DR: The successful development and operation of this portable PCR-CE system establishes the feasibility of rapid point-of-analysis DNA typing of forensic casework, of mass disaster samples or of individuals at a security checkpoint.
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Integrated DNA purification, PCR, sample cleanup, and capillary electrophoresis microchip for forensic human identification
TL;DR: A fully integrated microdevice and process for forensic short tandem repeat (STR) analysis has been developed that includes sequence-specific DNA template purification, polymerase chain reaction (PCR), post-PCR cleanup and inline injection, and capillary electrophoresis (CE).
Journal ArticleDOI
Integrated microfluidic systems for high-performance genetic analysis.
Peng Liu,Richard A. Mathies +1 more
TL;DR: This work discusses microfluidic integration in DNA sequencing, gene expression analysis, pathogen detection, and forensic short tandem repeat typing in formats that enable large-scale and point-of-analysis applications.