L
Leila Adamyan
Researcher at Moscow State University of Medicine and Dentistry
Publications - 133
Citations - 1416
Leila Adamyan is an academic researcher from Moscow State University of Medicine and Dentistry. The author has contributed to research in topics: Endometriosis & Medicine. The author has an hindex of 15, co-authored 115 publications receiving 1054 citations. Previous affiliations of Leila Adamyan include Moscow State University & Russian Academy.
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Journal ArticleDOI
Deep endometriosis: definition, diagnosis, and treatment
TL;DR: Deep endometriosis, defined as adenomyosis externa, is a rarely a progressive and recurrent disease, while bowel resection should be avoided, except for the sigmoid.
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Pathogenesis of endometriosis: the genetic/epigenetic theory
Philippe R. Koninckx,Anastasia Ussia,Leila Adamyan,Arnaud Wattiez,Victor Gomel,Dan C. Martin +5 more
TL;DR: The genetic epigenetic theory is compatible with all observations on endometriosis and a polygenetic/polyepigenetic mechanism is proposed to explain the hereditary aspects, the predisposition, and the endometiosis-associated changes in theendometrium, immunology, and placentation.
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Role of the peritoneal cavity in the prevention of postoperative adhesions, pain, and fatigue
TL;DR: Prevention of adhesion formation consists of the prevention of acute inflammation in the peritoneal cavity by means of gentle tissue handling, the addition of more than 5% N2O to the CO2 pneumoperitoneum, cooling the abdomen to 30°C, prevention of desiccation, a short duration of surgery, and, at the end of Surgery, meticulous hemostasis, thorough lavage, application of a barrier to injury sites, and administration of dexamethasone.
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Peritoneal full-conditioning reduces postoperative adhesions and pain: a randomised controlled trial in deep endometriosis surgery
TL;DR: This translational research confirms in the human the efficacy of FC in reducing CO2 resorption and adhesions with in addition less postoperative pain, lower postoperative CRP concentrations and an accelerated recovery.
Journal ArticleDOI
The epidemiology of endometriosis is poorly known as the pathophysiology and diagnosis are unclear.
Philippe R. Koninckx,Anastasia Ussia,Leila Adamyan,Muna Tahlak,Jörg Keckstein,Arnaud Wattiez,Dan C. Martin,Dan C. Martin +7 more
TL;DR: The oxidative stress of heavy menstrual bleeding with retrograde menstruation and an altered pelvic microbiome are probably associated with increasingly severe endometriosis, whether the prevalence is increasing, or whether endometiosis is associated with fat intake or an increased risk of cardiovascular disease is unclear.