Leon H. Zalkow

TL;DR: Observations suggested that esters at C-2' and/or C-7, which would tend to promote water solubility, might serve as useful prodrugs of taxol, and salts had improved antitumor activity as compared to the free acids.

TL;DR: A bioassay was developed to test the species-recognition hypothesis and the experimental results supporting the hypothesis suggest that cuticular hydrocarbons might serve as species- and caste- Recognition cues.

TL;DR: Azodicarbonamide (ADA) as mentioned in this paper is a new compound that inhibits HIV-1 and a broad range of retroviruses by targeting the nucleocapsid CCHC domains.

TL;DR: In this article, the extraction of taxol from the ground bark of Taxus brevifolia using supercritical carbon dioxide and carbon dioxide + ethanol mixtures was studied and the extractions were preformed at 318 K and at pressures ranging from 18.07 to 25.79 MPa.

TL;DR: In this paper, (+)-trachelanthic and (+)-viridifloric acids were synthesized and their isopropylidene derivatives were regiospecifically coupled, at C-9, with (-)-retronecine obtained by hydrolysis of monocrotaline, isolated from Crotalaria spectabilis.