L
Leonard A. Herzenberg
Researcher at Stanford University
Publications - 278
Citations - 28837
Leonard A. Herzenberg is an academic researcher from Stanford University. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 87, co-authored 278 publications receiving 27896 citations. Previous affiliations of Leonard A. Herzenberg include Santa Clara Valley Medical Center & Fairchild Semiconductor International, Inc..
Papers
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Journal ArticleDOI
Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens.
TL;DR: This paper used hybridoma monoclonal antibodies obtained after immunization of mice with rat cells to study rat cell-surface antigens present on subpopulations of rat lymphocytes.
Journal ArticleDOI
Gene transfer and molecular cloning of the rat nerve growth factor receptor.
TL;DR: The amino-acid sequence of one form of the receptor for nerve growth factor defines a new class of growth factor receptors, which are distinguished from previous classes of receptors based on their binding to growth factor.
Journal ArticleDOI
Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells
Brian Zambrowicz,Akira Imamoto,Steve Fiering,Leonard A. Herzenberg,William G. Kerr,Philippe Soriano +5 more
TL;DR: Staining of ROSA26 tissues and fluorescence-activated cell sorter-Gal analysis of hematopoietic cells demonstrates ubiquitous expression of the proviral beta geo reporter gene, and bone marrow transfer experiments illustrate the general utility of this strain for chimera and transplantation studies.
Journal ArticleDOI
Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man
Jeffrey A. Ledbetter,RL Evans,M Lipinski,C Cummingham-Rundles,R.A. Good,Leonard A. Herzenberg +5 more
TL;DR: The maintenance of the homologous molecules on functionally distinct T cell subpopulations in two evolutionarily distant species suggests that the Lyt and Leu antigens perform essential functions for the cells on which they are found.
Patent
Methods and transformed mammalian lymphocytic cells for producing functional antigen-binding protein including chimeric immunoglobulin and fragments
TL;DR: In this paper, the authors present methods for producing functional immunoglobulin using transfecting and expressing exogenous DNA coding for the heavy and light chains of the immunoglobalin.