L
Lesley C. Lewis-Alleyne
Researcher at University of Southern Mississippi
Publications - 2
Citations - 97
Lesley C. Lewis-Alleyne is an academic researcher from University of Southern Mississippi. The author has contributed to research in topics: Diimine & Skin cancer. The author has an hindex of 2, co-authored 2 publications receiving 88 citations.
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Journal ArticleDOI
Microwave synthesis of mixed ligand diimine–thiosemicarbazone complexes of ruthenium(II): biophysical reactivity and cytotoxicity
Floyd A. Beckford,Michael A. Shaloski,Gabriel LeBlanc,Jeffrey Thessing,Lesley C. Lewis-Alleyne,Alvin A. Holder,Liya Li,Navindra P. Seeram +7 more
TL;DR: A novel microwave-assisted synthetic method has been used to synthesise a series of mixed ligand ruthenium(II) compounds containing diimine as well as bidentate thiosemicarbazone ligands, which show good cytotoxic profiles against MCF-7 and MDA-MB-231 (breast adenocarcinoma) aswell as HCT 116 and HT-29 (colorectal carcinoma) cell lines.
Journal ArticleDOI
An in vitro study on the effect of synthesized tin(IV) complexes on glioblastoma, colorectal, and skin cancer cell lines
Jennie L. Williams,Lesley C. Lewis-Alleyne,Melinda Solomon,Long Nguyen,Robert Johnson,Jennifer Vital,Ping Ji,John Durant,Camille Cooper,Patrice Cagle,Patrick M. Martin,Don VanDerveer,William L. Jarrett,Alvin A. Holder +13 more
TL;DR: The overall effect of compounds 1-3 in the induction of appotosis and the inhibition of proliferation have defined an essential role for these compounds in chemotherapy.