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Lesley Colvin

Researcher at University of Dundee

Publications -  126
Citations -  4577

Lesley Colvin is an academic researcher from University of Dundee. The author has contributed to research in topics: Chronic pain & Population. The author has an hindex of 31, co-authored 113 publications receiving 3397 citations. Previous affiliations of Lesley Colvin include Edinburgh Cancer Research Centre & Edinburgh Royal Infirmary.

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Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews.

TL;DR: The quality of evidence was low due to participant numbers, length of intervention and follow‐up, and the evidence for any adverse effects or harm associated with physical activity and exercise interventions, though even these statistically significant results had only small‐to‐moderate effect sizes.
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Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia

TL;DR: Clinical and mechanism-based understanding of tolerance and opioid-induced hyperalgesia are focused on, current and future strategies for pain management are discussed, and alternatives include inhibition of peripheral μ opioid receptors and blockade of downstream signalling mechanisms.
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Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis.

TL;DR: The objective of this work was to study the prevalence of pain syndromes in MS both cross‐sectionally, and longitudinally during the MS disease course, and to systematically identify prospective studies detailing pain prevalence in definite MS.
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Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review

TL;DR: Combined therapies may well be required for most effective management of chemotherapy induced peripheral neuropathy, and the role of mitochondrial dysfunction, oxidative stress, immune cells and changes in ion channels is focused on from summary of the latest literature in these areas.