L
Leszek Kaczmarek
Researcher at Nencki Institute of Experimental Biology
Publications - 322
Citations - 17426
Leszek Kaczmarek is an academic researcher from Nencki Institute of Experimental Biology. The author has contributed to research in topics: Gene expression & Synaptic plasticity. The author has an hindex of 67, co-authored 302 publications receiving 15985 citations. Previous affiliations of Leszek Kaczmarek include McGill University & University of California, Los Angeles.
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The involvement of the anterior cingulate cortex in remote contextual fear memory
TL;DR: In this article, the anterior cingulate cortex plays a critical role in remote memory for contextual fear conditioning, and reversible inactivation of this structure in normal mice disrupts remote memory without affecting recent memory.
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Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory.
Vanja Nagy,Ozlem Bozdagi,Anna Matynia,Marcin Balcerzyk,Pawel Okulski,Joanna Dzwonek,Rui M. Costa,Alcino J. Silva,Leszek Kaczmarek,George W. Huntley +9 more
TL;DR: A novel role for MMP-9 is demonstrated in hippocampal synaptic physiology, plasticity, and memory and integrin function-blocking reagents prevent an M MP-9-mediated potentiation of synaptic signal strength.
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Estrogen receptor β: Potential functional significance of a variety of mRNA isoforms
TL;DR: It is proposed that the diversity of ERβ isoforms implies a functional role of this phenomenon in cellular physiology and pathology of estrogen response, and the great variation in isoform structure among various mammalian species is found.
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Matrix Metalloproteinase-9 Undergoes Expression and Activation during Dendritic Remodeling in Adult Hippocampus
TL;DR: A unique spatiotemporal pattern of MMP-9 expression suggests its involvement in activity-dependent remodeling of dendritic architecture with possible effects on synaptic physiology.
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A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK?
Ewelina Knapska,Leszek Kaczmarek +1 more
TL;DR: It is suggested that Zif268 expression and function should be considered in a context of neuronal activity that is tightly linked to neuronal plasticity.