L
Li Li
Researcher at National Institutes of Health
Publications - 1
Citations - 4669
Li Li is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Interleukin 21 & CD28. The author has an hindex of 1, co-authored 1 publications receiving 4410 citations.
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Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3
Wanjun Chen,Wenwen Jin,Neil J. Hardegen,Ke Jian Lei,Li Li,Nancy J. Marinos,George McGrady,Sharon M. Wahl +7 more
TL;DR: Novel evidence is presented that conversion of naive peripheral CD4+CD25− T cells into anergic/suppressor cells that are CD25+, CD45RB−/low and intracellular CTLA-4+ can be achieved through costimulation with T cell receptors (TCRs) and transforming growth factor β (TGF-β).