L
Li Lin
Researcher at Southern Medical University
Publications - 38
Citations - 1462
Li Lin is an academic researcher from Southern Medical University. The author has contributed to research in topics: Cancer & Cell growth. The author has an hindex of 17, co-authored 35 publications receiving 1178 citations.
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Journal ArticleDOI
The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1.
Yang Zhao,Yajing Liu,Li Lin,Qiong Huang,Wanming He,Shuyi Zhang,Shumin Dong,Zhaowei Wen,Jinjun Rao,Wangjun Liao,Min Shi +10 more
TL;DR: Elevated expression of MACC1-AS1 in gastric cancer tissues is linked to poor prognosis and promotes malignant phenotype upon cancer cells, and this was suggested to be coordinated by the AMPK/Lin28 pathway.
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Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis.
TL;DR: MALAT1 can promote tumorigenicity and metastasis in GC by facilitating VM and angiogenesis via the VE-cadherin/β-catenin complex and ERK/MMP and FAK/paxillin signaling pathways.
Journal ArticleDOI
XB130 promotes proliferation and invasion of gastric cancer cells
Min Shi,Dayong Zheng,Li Sun,Lin Wang,Li Lin,Yajun Wu,Minyu Zhou,Wenjun Liao,Yulin Liao,Qiang Zuo,Wangjun Liao +10 more
TL;DR: Findings indicate that XB 130 enhances cell motility and invasiveness by modulating the EMT-like process, while silencing XB130 in GC suppresses tumorigenesis and metastasis, suggesting that it may be a potential therapeutic target.
Journal ArticleDOI
Metastasis‐associated in colon cancer‐1 upregulation predicts a poor prognosis of gastric cancer, and promotes tumor cell proliferation and invasion
Lin Wang,Yajun Wu,Li Lin,Pengmin Liu,Hui Huang,Wenjun Liao,Dayong Zheng,Qiang Zuo,Li Sun,Na Huang,Min Shi,Yulin Liao,Wangjun Liao +12 more
TL;DR: Findings provide some novel insights into the role of MACC1, a gene that contributes to a poor prognosis of GC by promoting tumor cell proliferation and invasion as well as the EMT.
Journal ArticleDOI
MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling.
Na Huang,Zhenzhen Wu,Li Lin,Minyu Zhou,Lin Wang,Huanrong Ma,Jianling Xia,Jianping Bin,Yulin Liao,Wangjun Liao +9 more
TL;DR: It is shown that miR-338-3p inhibited the migration and invasion of GC cells in vitro and directly targeted zinc finger E-box-binding protein 2 (ZEB2) and metastasis-associated in colon cancer-1 (MACC1).