L
Li Xiao
Researcher at The Nippon Dental University
Publications - 33
Citations - 1139
Li Xiao is an academic researcher from The Nippon Dental University. The author has contributed to research in topics: Oxidative stress & HaCaT. The author has an hindex of 17, co-authored 31 publications receiving 932 citations. Previous affiliations of Li Xiao include Prefectural University of Hiroshima & Hiroshima University.
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Antioxidant effects of water-soluble fullerene derivatives against ultraviolet ray or peroxylipid through their action of scavenging the reactive oxygen species in human skin keratinocytes.
TL;DR: In this paper, PEG-modified fullerene, hydroxy-fullerene and isostearate-mixed fullerenes were shown to scavenge reactive oxygen species (ROS) in the nuclei of UVB-irradiated human skin HaCaT.
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ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?
TL;DR: The role of ACE2 in the pathogenesis of severe and critical conditions of COVID-19 is explained and auspicious strategies for controlling the disease are discussed.
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The water-soluble fullerene derivative "Radical Sponge" exerts cytoprotective action against UVA irradiation but not visible-light-catalyzed cytotoxicity in human skin keratinocytes.
TL;DR: Cytoprotection by Radical Sponge against UVA was achieved at the advisable range doses of 10-40 microM in contrast to no effect of polyvinylpyrrolidone alone; its dose- dependency was advantageous over that of VC-IP, a tetra-alkyl-esterized provitamin C, which became less cytoprotective above 20 microM.
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From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
Li Xiao,Masanori Nasu +1 more
TL;DR: Experimental and clinical data indicate that the cell sheets can not only safely and effectively reconstruct the damaged cornea in humans, but also repair esophageal ulcer in animal models.
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Inhibitory effect of the water-soluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues.
TL;DR: Radical Sponge showed to significantly inhibit UVA-promoted melanogenesis in normal human epidermis melanocytes and human melanoma HMV-II cells within a non-cytotoxicity dose range, and demonstrated the stronger anti-melanogenic potential according to spectrophotometric quantification for extracted melanin.