L
Li Yang
Researcher at Sichuan University
Publications - 371
Citations - 6789
Li Yang is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 35, co-authored 295 publications receiving 4474 citations.
Papers
More filters
Journal ArticleDOI
Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors
Zhen Fang,Tianqi Wang,Hui Li,Guo Zhang,Xiao-Ai Wu,Li Yang,Yu-lan Peng,Jun Zou,Lin-Li Li,Rong Xiang,Shengyong Yang +10 more
TL;DR: Overall, compound 10r could be taken as a good lead compound for further studies and is the most potent one with an IC50 value of 0.41±0.03μM against KDM4D.
Journal ArticleDOI
Microenvironment-responsive multifunctional hydrogels with spatiotemporal sequential release of tailored recombinant human collagen type III for the rapid repair of infected chronic diabetic wounds.
Cheng Hu,Wenqi Liu,Linyu Long,Zhicun Wang,Yihui Yuan,Wen Zhang,ShuYi He,Jian Wang,Li Yang,Lu Lu,Yunbing Wang +10 more
TL;DR: Wang et al. as discussed by the authors presented a tailored recombinant human collagen type III (rhCol III) and constructed a multifunctional microenvironment-responsive hydrogel carrier based on multifunctionAL antibacterial nanoparticles (PDA@Ag NPs).
Journal ArticleDOI
A thrombin-triggered self-regulating anticoagulant strategy combined with anti-inflammatory capacity for blood-contacting implants
Yanan Wang,Haoshuang Wu,Zhonghe Zhou,Manfred F. Maitz,Kun Liu,Bo Zhang,Li Yang,Rifang Luo,Yunbing Wang +8 more
TL;DR: It was demonstrated that the coating worked as a precise strategy to resist coagulation and inflammation, escorted reendothelialization on the cardiovascular devices, and provided a new perspective for designing endothelium-like functional coatings.
Journal ArticleDOI
Sustained and targeted delivery of siRNA/DP7-C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy
Binyan Zhao,Bailing Zhou,Kun Shi,Rui Zhang,Chunyan Dong,Daoyuan Xie,Lin Tang,Yaomei Tian,Zhiyong Qian,Li Yang +9 more
TL;DR: Wang et al. as discussed by the authors showed that Pin1 siRNA is an efficient method for the treatment of hepatocellular carcinoma cells and provides a sustainable and effective drug delivery system for the suppression of liver cancer.
Journal ArticleDOI
The synthesis, structure-toxicity relationship of cisplatin derivatives for the mechanism research of cisplatin-induced nephrotoxicity.
TL;DR: The potency of biotin-pyridine conjugated derivative 3 met the requirement for target identification, and the preliminary chemical proteomics results suggested that it is a promising tool for further target identification of cisplatin-induced nephrotoxicity.