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Cheng Hu

Researcher at Sichuan University

Publications -  51
Citations -  1372

Cheng Hu is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Self-healing hydrogels. The author has an hindex of 12, co-authored 35 publications receiving 468 citations.

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Dual-crosslinked mussel-inspired smart hydrogels with enhanced antibacterial and angiogenic properties for chronic infected diabetic wound treatment via pH-responsive quick cargo release

TL;DR: The mechanisms by which the designed hydrogels accelerated the healing of bacterial infected diabetic wounds in vitro and in vivo were elucidated, and they represented a general strategy for the Healing of a wide range of tissue injuries.
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Dual-responsive injectable hydrogels encapsulating drug-loaded micelles for on-demand antimicrobial activity and accelerated wound healing.

TL;DR: A smart pH- and reactive oxygen species (ROS)-responsive injectable hydrogel with self-healing and remodeling capability was designed and showed good biocompatibility, and greatly promoted the healing of infected wounds in vitro by cell scratch assay.
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Inflammation-Responsive Drug-Loaded Hydrogels with Sequential Hemostasis, Antibacterial, and Anti-Inflammatory Behavior for Chronically Infected Diabetic Wound Treatment.

TL;DR: In this paper, a dual-responsive (pH and reactive oxygen species (ROS)) hydrogel was prepared to realize drug release properties under inflammatory stimulation by grafting 3-carboxy-phenylboronic acid to the gelatin molecular backbone and cross-linking with poly(vinyl alcohol).
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Virion-Like Membrane-Breaking Nanoparticles with Tumor-Activated Cell-and-Tissue Dual-Penetration Conquer Impermeable Cancer.

TL;DR: This work provides the first demonstration of sophisticated molecular and supramolecular engineering of virion‐like MBNs to realize the long‐awaited cell‐and‐tissue dual‐penetration, contributing to the development of a brand‐new avenue for dealing with incurable cancers.
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Synergistic Chemical and Photodynamic Antimicrobial Therapy for Enhanced Wound Healing Mediated by Multifunctional Light-Responsive Nanoparticles.

TL;DR: Light-responsive multifunctional nanoparticles with conjugation of quaternary ammonium chitosan and photosensitizer chlorin e6 (Ce6) to merge chemical and photodynamic therapy to efficient anti-bacteria to represent a promising class of antimicrobial strategy for potential clinical translation.