L
Liang Kung Chen
Researcher at Taipei Veterans General Hospital
Publications - 399
Citations - 15896
Liang Kung Chen is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 44, co-authored 337 publications receiving 11136 citations. Previous affiliations of Liang Kung Chen include Chia Nan University of Pharmacy and Science & National Yang-Ming University.
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Journal ArticleDOI
Prevalence of the prescribing of potentially inappropriate medications at ambulatory care visits by elderly patients covered by the Taiwanese National Health Insurance program.
TL;DR: There was a high prevalence of the prescribing of potentially inappropriate medications at ambulatory care visits by elderly patients in Taiwan in 2001-2004 and its influence on health care resource utilization was investigated.
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Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway.
Kun Ling Tsai,Li Hsin Chen,Shih Hwa Chiou,Guang-Yuh Chiou,Yu Chih Chen,Hsiang Yun Chou,Liang Kung Chen,Hsiao Yun Chen,Tsan Hung Chiu,Chiou Sheng Tsai,Hsiu Chung Ou,Chung Lan Kao +11 more
TL;DR: These results provide new highlight onto the possible molecular mechanisms of how Co Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway.
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Reduced cerebellar gray matter is a neural signature of physical frailty.
Wei Ta Chen,Kun Hsien Chou,Li Kuo Liu,Li Kuo Liu,Pei Lin Lee,Wei Ju Lee,Liang Kung Chen,Liang Kung Chen,Pei Ning Wang,Ching Po Lin +9 more
TL;DR: It is concluded that physical frailty is associated with a decreased reserve in specific brain regions, especially cerebellum, and further longitudinal studies are needed to explore if the cerebellar‐ and noncerebellum‐based frailty components reflect a distinctive future risk for developing frailty.
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A persistent level of Cisd2 extends healthy lifespan and delays aging in mice
Chia Yu Wu,Yi-Fan Chen,Chih Hao Wang,Cheng Heng Kao,Hui Wen Zhuang,Chih-Cheng Chen,Liang Kung Chen,Ralph Kirby,Yau-Huei Wei,Shih-Feng Tsai,Ting Fen Tsai +10 more
TL;DR: It is demonstrated that a persistent level of Cisd2 achieved by transgenic expression in mice extends their median and maximum lifespan without any apparent deleterious side effects and suggests that Cisd 2 is a fundamentally important regulator of lifespan.
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Cognitive Function in Individuals With Physical Frailty but Without Dementia or Cognitive Complaints: Results From the I-Lan Longitudinal Aging Study.
Yi Hui Wu,Yi Hui Wu,Li Kuo Liu,Li Kuo Liu,Wei Ta Chen,Wei Ta Chen,Wei Ju Lee,Wei Ju Lee,Li Ning Peng,Li Ning Peng,Pei Ning Wang,Pei Ning Wang,Liang Kung Chen,Liang Kung Chen +13 more
TL;DR: Even without subjective cognitive complaints, higher risk of cognitive impairment is presented in the prefrail and frail individuals and the incremental impact of frailty on cognition and the susceptibility of nonmemory domain may provide a new view in evaluating the pathogenesis of the relationship between frailty and cognitive impairment.