Liliana Spina

TL;DR: It is speculated that drug addiction results from the impact exerted on behavior by the abnormal DA stimulant properties acquired by drug-conditioned stimuli as a result of their association with addictive drugs.

TL;DR: To investigate the relative role of central delta- and mu- opioid receptors in behavior, the effects of (D-Ala2)deltorphin II and PL017, a natural delta-opioid peptide and a beta-casomorphin derivative specific for mu receptors, were compared after local intracerebral and intraventricular administration.

TL;DR: The hypothesis that stimulation of D-1 receptors exerts a permissive role for the expression of behavioral stimulation following D-2 receptor stimulation is supported, as well as the ability of apomorphine to induce stereotypies in alpha-MT pretreated rats.

TL;DR: A wealth of experimental evidence is presented that converges to suggest that acetaldehyde is an intrinsically active compound, is metabolically generated in the brain and mediates many of the psychopharmacological properties of ethanol.

TL;DR: Investigating the role of DA D1 and D2 receptors of the rat NAc shell and core in the motivational effects of nicotine using a conditioned place preference (CPP) paradigm indicates that dopamine D1 but not D2 receptor of theNAc shell are specifically involved in the acquisition of nicotine-induced CPP.