L
Limin Lu
Researcher at Fudan University
Publications - 54
Citations - 1656
Limin Lu is an academic researcher from Fudan University. The author has contributed to research in topics: Angiotensin II & Kidney. The author has an hindex of 21, co-authored 51 publications receiving 1279 citations. Previous affiliations of Limin Lu include Fudan University Shanghai Medical College & Shanghai Jiao Tong University.
Papers
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Journal ArticleDOI
Renal Medullary MicroRNAs in Dahl Salt-Sensitive Rats: miR-29b Regulates Several Collagens and Related Genes
Yong Liu,Norman E. Taylor,Limin Lu,Kristie Usa,Allen W. Cowley,Nicholas R. Ferreri,Nan Cher Yeo,Mingyu Liang +7 more
TL;DR: Broad effects of miR-29b on a large number of collagens and genes related to the extracellular matrix are demonstrated and suggested involvement in the protection from renal medullary injury in SS-13BN rats.
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The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury
Naijun Miao,Fan Yin,Hongyan Xie,Yanzhe Wang,Yiang Xu,Yang Shen,Dan Xu,Jianyong Yin,Bao Wang,Z. Zhou,Qian Cheng,Panpan Chen,Hong Xue,Li Zhou,Jun Liu,Xiaoxia Wang,Wei Zhang,Limin Lu +17 more
TL;DR: This study indicates that caspase-11/GSDMD dependent tubule cell pyroptosis plays a significant role in initiating tubular cell damage, urinary IL-18 excretion and renal functional deterioration in AKI.
Journal ArticleDOI
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide
Ping Yuan,Hong Xue,Li Zhou,Lin-ping Qu,Cheng Li,Zhen Wang,Jun Ni,Chen Yu,Tai Yao,Yu Huang,Rui Wang,Rui Wang,Limin Lu +12 more
TL;DR: Suppressed CSE-catalyzed endogenous H(2)S production in the kidney by hyperglycemia may play an important role in the pathogenesis of DN.
Journal ArticleDOI
Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy.
Qian Cheng,Jing Pan,Z. Zhou,Fan Yin,Hongyan Xie,Panpan Chen,Jingyao Li,Peiqing Zheng,Li Zhou,Wei Zhang,Jun Liu,Limin Lu +11 more
TL;DR: It is demonstrated that caspase-11/4 and GSDMD-mediated pyroptosis is activated and involved in podocyte loss under hyperglycemia condition and the development of DN.
Journal ArticleDOI
H2S Inhibits Hyperglycemia-Induced Intrarenal Renin-Angiotensin System Activation via Attenuation of Reactive Oxygen Species Generation
Hong Xue,Ping Yuan,Ping Yuan,Jun Ni,Chen Li,Decui Shao,Jia Liu,Yang Shen,Zhen Wang,Li Zhou,Wei Zhang,Yu Huang,Chen Yu,Rui Wang,Rui Wang,Limin Lu +15 more
TL;DR: Data suggested that the decrease in H2S under hyperglycemic condition leads to an imbalance between oxidative and reductive species, which, in turn, contributes to the pathogenesis of renal dysfunction.