Lin Wang

TL;DR: A case-control-based GWAS followed by two rounds of replication is conducted to elucidate the genetic architecture of NSCL/P in China and provides additional evidence that the rs2235371-related haplotype at 1q32.2 could play a more important role than the previously identified causal variant rs642961 in Chinese populations.

TL;DR: Levels in human blood and tumor tissues are associated with CRC cancer occurrence, metastasis and drug resistance, and miR-143 levels may be used as a new diagnostic marker and therapeutic target for CRC in the future.

TL;DR: MIR152 is reported as a new autophagy-regulating miRNA that plays a role in cisplatin-resistance and it is found that EGR1 (early growth response 1) regulated the MIR152 gene at the transcriptional level.

TL;DR: It is demonstrated that miR-143 plays a significant role in inactivating the RAS signaling pathway through the inhibition of N-RAS, which may provide a novel therapeutic strategy for treatment of glioma and other RAS-driven cancers.

TL;DR: MiR-124 levels in tumor tissues are associated with glioma occurrence, angiogenesis, and chemoresistance and that miR- 124 may be used as a new diagnostic marker and therapeutic target forglioma in the future.