L
Lindsay Lane
Publications - 1
Citations - 116
Lindsay Lane is an academic researcher. The author has contributed to research in topics: Liver X receptor & Cholesterol. The author has an hindex of 1, co-authored 1 publications receiving 107 citations.
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Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking.
Jessie Zhang,Trey Coleman,S. Joshua Langmade,David E. Scherrer,Lindsay Lane,M. Hunter Lanier,Chu Feng,Mark S. Sands,Jean E. Schaffer,Clay F. Semenkovich,Daniel S. Ory +10 more
TL;DR: The results demonstrate that NPC1 serves an atheroprotective role in mice through regulation of LXR-dependent cholesterol efflux and mitigation of cholesterol-induced oxidative stress in macrophages.