L
Lindsey Law
Researcher at Johns Hopkins University
Publications - 1
Citations - 364
Lindsey Law is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Nitric oxide synthase & Endothelial NOS. The author has an hindex of 1, co-authored 1 publications receiving 334 citations.
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GAPDH mediates nitrosylation of nuclear proteins
Michael D. Kornberg,Nilkantha Sen,Makoto R. Hara,Makoto R. Hara,Krishna R. Juluri,Judy V. Nguyen,Adele M. Snowman,Lindsey Law,Lynda D. Hester,Solomon H. Snyder +9 more
TL;DR: It is shown that SNO–GAPDH physiologically transnitrosylates nuclear proteins, including the deacetylating enzyme sirtuin-1 (SIRT1), histone de acetylase-2 (HDAC2) and DNA-activated protein kinase (DNA-PK), which suggest that protein–protein transfer of nitric oxide groups may be a general mechanism in cellular signal transduction.