L
Ling Mei
Researcher at Sichuan University
Publications - 35
Citations - 1418
Ling Mei is an academic researcher from Sichuan University. The author has contributed to research in topics: Drug delivery & In vivo. The author has an hindex of 19, co-authored 32 publications receiving 1057 citations. Previous affiliations of Ling Mei include University of Michigan.
Papers
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Journal ArticleDOI
Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting.
Yayuan Liu,Rui Ran,Jiantao Chen,Qifang Kuang,Jie Tang,Ling Mei,Qianyu Zhang,Huile Gao,Zhirong Zhang,Qin He +9 more
TL;DR: R8-RGD-lipo was proved to be a potential anti-glioma drug delivery system and a promising ligand possessing multi functions including BBB transporting, glioma targeting and tumor penetrating.
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Synergistic dual-ligand doxorubicin liposomes improve targeting and therapeutic efficacy of brain glioma in animals.
Taili Zong,Ling Mei,Huile Gao,Wei Cai,Pengjin Zhu,Kairong Shi,Jiantao Chen,Yang Wang,Fabao Gao,Qin He +9 more
TL;DR: The dual-ligand liposomes comodified with T7 and TAT possessed strong capability of synergistic targeted delivery of payload into tumor cells both in vitro and in vivo, and they were able to improve the therapeutic efficacy of brain glioma in animals.
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Increased tumor targeted delivery using a multistage liposome system functionalized with RGD, TAT and cleavable PEG
Ling Mei,Ling Fu,Kairong Shi,Qianyu Zhang,Yayuan Liu,Jie Tang,Huile Gao,Zhirong Zhang,Qin He +8 more
TL;DR: A multistage liposome system co-modified with RGD, TAT and cleavable PEG that combined the advantages of PEG, specific ligand and penetrating peptide for efficient delivery to tumor tissue and selective internalization into tumor cells is designed.
Journal ArticleDOI
Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy
Yayuan Liu,Ling Mei,Chaoqun Xu,Qianwen Yu,Kairong Shi,Li Zhang,Yang Wang,Qianyu Zhang,Huile Gao,Zhirong Zhang,Qin He +10 more
TL;DR: R8-dGR was an ideal dual receptor recognizing CPP with selective glioma targeting and efficient intratumoral diffusion, which could be further used to equip drug delivery system for effectiveglioma therapy.
Journal ArticleDOI
Multifunctional Tandem Peptide Modified Paclitaxel-Loaded Liposomes for the Treatment of Vasculogenic Mimicry and Cancer Stem Cells in Malignant Glioma.
Yayuan Liu,Ling Mei,Qianwen Yu,Chaoqun Xu,Yue Qiu,Yuting Yang,Kairong Shi,Qianyu Zhang,Huile Gao,Zhirong Zhang,Qin He +10 more
TL;DR: R8-c(RGD)-Lip was a safe and efficient antiglioma drug delivery system used for the treatment of glioma and demonstrated both anti-VM and anti-BCSC effects in vivo.