Lisa Chung

TL;DR: The current state of SRM/MRM software tools is reviewed and future directions of these software tools are discussed in order to enable researchers to combine these tools for a comprehensive targeted proteomics workflow.

TL;DR: It is demonstrated that in 28-day-old juvenile mice, BDS impairs synaptic maturation and reduces the expression of proteins that are necessary for axonal growth, myelination, and mitochondrial function, and these results add two important findings to previous work in the field.

TL;DR: Phosphorylation events that are bidirectionally regulated by the reconsolidation versus extinction of a cocaine-associated memory, including a novel site on CaMKIIα are identified, and using a rodent model of addiction, it is shown that Ca MKII inhibition in the amygdala can reduce relapse-like behavior.

TL;DR: A high-throughput method based on a novel gene expression analysis, RNA-Seq, is used to give a global picture of differential gene expression by primary human macrophages of 10 healthy donors infected in vitro with WNV.

TL;DR: Since human urine is the most readily available biofluid whose proteome changes in response to disease, it is a logical sample for identifying protein biomarkers for kidney diseases.