Lisa Susswein

TL;DR: The consistent findings regarding the role of VKORC1 and CYP2C9 in warfarin metabolism and maintenance dosage represent a clinically useful proof of principal for the use of pharmacogenomic information in medicine and may lead to improved understanding of warFarin’s actions.

TL;DR: For example, this paper found that African American women were less likely to enroll in the cancer genetics registry than white women. But, the only significant predictor of enrolment in multivariable models was race.

TL;DR: There is no single correct approach, but recommend a balanced approach that takes into account the nature of the particular study as well as its recruitment goals, and a framework for considering alternative recruitment strategies and their implications.

TL;DR: Supportive results for the routine provision of BRCA1/2 genetic test results by telephone are found and suggest that test results should be delivered as swiftly as possible once available and that offering patients a choice of how to receive results is desirable.

TL;DR: African American race was associated with an overall decreased uptake of BRCA1/2 genetic testing, even when barriers of ascertainment and cost were minimized, however, among African American women, a recent diagnosis of breast cancer wasassociated with substantially increased uptake of testing.