Liselotte Dahlgren

TL;DR: HPV‐16 is mainly episomal in tonsillar cancer, the viral load showed a wide distribution and the clinical outcome in this study was better when the HPV load was higher.

TL;DR: HPV is significantly more common in base of tongues cancer than in mobile tongue cancer, and has a positive impact on disease‐specific survival in patients with base of tongue cancer.

TL;DR: As expected, patients with an HPV‐positive tumor had a statistically significantly better disease‐specific survival than patients with a HPV‐negative tumor, and the most common changes, e.g., gain on 3q or 8q, loss on 11q or 13 and loss on chromosome 7q in HPV‐ negative tumors, did not have any influence on prognosis.

TL;DR: HPV-positive cancer exhibits less genetic instability i.e. shows a lower degree of aneuploidy and a tendency to have fewer chromosomal aberrations, when compared to HPV-negative tonsillar cancer.

TL;DR: HPV is rarely detected in primary malignant melanomas of non-sun exposed body areas and no samples were positive according to all five defined criteria for HPV positivity although two werepositive according to 4/5 criteria.