L
Lluis Castells
Researcher at Carlos III Health Institute
Publications - 113
Citations - 5987
Lluis Castells is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 29, co-authored 104 publications receiving 5373 citations. Previous affiliations of Lluis Castells include Hebron University & Autonomous University of Barcelona.
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Journal ArticleDOI
Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis
Pau Sort,Miquel Navasa,Vicente Arroyo,Xavier Aldeguer,Ramon Planas,Luis Ruiz-del-Arbol,Lluis Castells,Victor Vargas,Germán Soriano,Mónica Guevara,Pere Ginès,Joan Rodés +11 more
TL;DR: In patients with cirrhosis and spontaneous bacterial peritonitis, treatment with intravenous albumin in addition to an antibiotic reduces the incidence of renal impairment and death in comparison with treatment with an antibiotic alone.
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Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics.
Maria Varela,Maria Isabel Real,Marta Burrel,Alejandro Forner,Margarita Sala,Mercè Brunet,Carmen Ayuso,Lluis Castells,Xavier Montaña,Josep M. Llovet,Jordi Bruix +10 more
TL;DR: Chemoembolization using DEBs is an effective procedure with a favorable pharmacokinetic profile and after a median follow-up of 27.6 months, 1- and 2-year survival is 92.5% and 88.9%, respectively.
Journal ArticleDOI
Randomized controlled trial of interferon treatment for advanced hepatocellular carcinoma.
Josep M. Llovet,Margarita Sala,Lluis Castells,Yanette Suarez,Ramón Vilana,Lluís Bianchi,Carmen Ayuso,Victor Vargas,Joan Rodés,Jordi Bruix +9 more
TL;DR: The results indicate that IFN is not properly tolerated in patients with cirrhosis and advanced HCC and that its administration prompts no benefit in terms of tumor progression rate and survival.
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Randomized, comparative study of oral ofloxacin versus intravenous cefotaxime in spontaneous bacterial peritonitis
Miquel Navasa,A Follo,Josep M. Llovet,Gerardo Clemente,Victor Vargas,Antonio Rimola,Francesc Marco,Carlos Guarner,Montserrat Forné,Ramon Planas,Rafael Bañares,Lluis Castells,M. T. Jimenez de Anta,V. Arroyo,Joan Rodés +14 more
TL;DR: Nonazotemic cirrhotic patients with uncomplicated community-acquired spontaneous bacterial peritonitis and without hepatic encephalopathy have an excellent prognosis and may be treated with oral ofloxacin without requiring hospitalization, as well as intravenous cefotaxime in this infection.
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The development of low-grade cerebral edema in cirrhosis is supported by the evolution of 1H-magnetic resonance abnormalities after liver transplantation
Juan Córdoba,Juli Alonso,Alex Rovira,Carlos Jacas,Francesc Sanpedro,Lluis Castells,Victor Vargas,Carles Margarit,Jaime Kulisewsky,Rafael Esteban,Jaume Guardia +10 more
TL;DR: Cirrhotic patients show reversible changes in magnetization transfer ratio that are compatible with the development of low-grade cerebral edema, which appear to be the consequences of the metabolism of ammonia in the brain.