L
Loralie J. Langman
Researcher at Mayo Clinic
Publications - 74
Citations - 1822
Loralie J. Langman is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Therapeutic drug monitoring & Pharmacogenomics. The author has an hindex of 20, co-authored 71 publications receiving 1288 citations.
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Journal ArticleDOI
The challenges of personalized medicine.
Journal ArticleDOI
Effect of Cytochrome P450 Enzyme Polymorphisms on Pharmacokinetics of Venlafaxine
Donald E. McAlpine,Joanna M. Biernacka,David A. Mrazek,Dennis J. O'Kane,Susanna R. Stevens,Loralie J. Langman,Vicki L Courson,Jyoti Bhagia,Thomas P. Moyer +8 more
TL;DR: Both CYP2D6 and CYC19 genotypes should be considered when using pharmacogenomic information for venlafaxine dose alterations, due to their influence on the total concentration of the active compounds venl Lafaxine and ODV.
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Toxicology: then and now.
Loralie J. Langman,Bhushan Kapur +1 more
TL;DR: The historical progress of clinical and forensic toxicology is reviewed by exploring analytical techniques in drug analysis, differing biological matrices, clinical toxicology, therapeutic drug management, workplace drug testing, and pharmacodynamic monitoring and pharmacogenetics.
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Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study.
John T. Bernert,Peyton Jacob,David Holiday,Neal L. Benowitz,Connie S. Sosnoff,Mira Doig,Colin Feyerabend,Kenneth M. Aldous,Mehran Sharifi,Mark D. Kellogg,Loralie J. Langman +10 more
TL;DR: Methods of chromatographic analysis of serum cotinine, as used by these experienced laboratories, are capable of providing accurate and precise results in both the smoker and the nonsmoker concentration range.
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Detection of synthetic cannabinoids in herbal incense products.
TL;DR: Synthetic cannabinoids are present in herbal incense purchased over the internet and a broad class GC/MS drug screening method detected JWH-018 andJWH-073 in methanolic extracts and teas steeped from herbal incENSE products in three of four products tested.