L
Loralie J. Langman
Researcher at Mayo Clinic
Publications - 74
Citations - 1822
Loralie J. Langman is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Therapeutic drug monitoring & Pharmacogenomics. The author has an hindex of 20, co-authored 71 publications receiving 1288 citations.
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Journal ArticleDOI
Volumetric Microsampling of Capillary Blood Spot vs Whole Blood Sampling for Therapeutic Drug Monitoring of Tacrolimus and Cyclosporin A: Accuracy and Patient Satisfaction.
Michael M. Mbughuni,Maria A. Stevens,Loralie J. Langman,Yogish C. Kudva,William Sanchez,Patrick G. Dean,Paul J. Jannetto +6 more
TL;DR: An abbreviated method validation of the Mitra Microsampling Device is reported including: accuracy, precision, linearity, carry-over, and stability using residual venous whole blood (VB) samples.
Journal ArticleDOI
Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine.
Lanqing Wang,John T. Bernert,Neal L. Benowitz,June Feng,Peyton Jacob,Ernest McGahee,Samuel P. Caudill,Gerhard Scherer,Max Scherer,Nikola Pluym,Mira Doig,Kirk Newland,Sharon E. Murphy,Nicolas J. Caron,Lane C. Sander,Makiko Shimizu,Hiroshi Yamazaki,Sung Kim,Loralie J. Langman,Jeanita S. Pritchett,Lorna T. Sniegoski,Yao Li,Yao Li,Benjamin C. Blount,James L. Pirkle +24 more
TL;DR: This evaluation indicates that the experienced laboratories participating in this study can produce reliable and comparable human urinary nicotine metabolic profiles in samples from people with significant recent exposure to nicotine.
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The development and validation of a turbulent flow-liquid chromatography–tandem mass spectrometric method for the simultaneous quantification of citalopram, sertraline, bupropion and hydroxybupropion in serum
Athena K. Petrides,Joshua Moskowitz,Kamisha L. Johnson-Davis,Paul J. Jannetto,Loralie J. Langman,William Clarke,Mark A. Marzinke +6 more
TL;DR: A turbulent flow-liquid chromatography-tandem mass spectrometric (TFC-MS/MS) method for the robust, simultaneous quantification of citalopram, sertraline, bupropion and its active metabolite, hydroxyb upropion (OH-bupropion).
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High-throughput online solid-phase extraction tandem mass spectrometry: Is it right for your clinical laboratory?
TL;DR: The Agilent RapidFire 365 Mass Spectrometry system works well for several classes of medications including immunosuppressants, anticonvulsants and antineoplastic agents where dosage adjustments are made to maximize efficacy and minimize toxicity once results are available.
Journal ArticleDOI
Therapeutic dose monitoring of mycophenolate mofetil in dermatologic diseases
TL;DR: Monitoring MPA levels can help the dermatologist to increase the dose in patients who have poor absorption or to detect therapeutic noncompliance, and is recommended only in patients not responding to the standard 2-g/d dosage of MMF.