L
Loredana Salito
Researcher at University of Catania
Publications - 5
Citations - 339
Loredana Salito is an academic researcher from University of Catania. The author has contributed to research in topics: microRNA & Transcriptome. The author has an hindex of 5, co-authored 5 publications receiving 316 citations.
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Journal ArticleDOI
Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.
Davide Barbagallo,Angelo Giuseppe Condorelli,Marco Ragusa,Loredana Salito,Mariangela Sammito,Barbara Banelli,Rosario Caltabiano,Giuseppe Barbagallo,Agata Zappalà,Rosalia Battaglia,Matilde Cirnigliaro,Salvatore Lanzafame,E Vasquez,Rosalba Parenti,Federico Cicirata,Cinzia Di Pietro,Massimo Romani,Michele Purrello +17 more
TL;DR: It is proposed that the axis miR-671-5p /CDR1-AS / CDR1 / VSNL1 is functionally altered in GBM cells and is involved in the modification of their biopathological profile.
Journal ArticleDOI
Specific Alterations of MicroRNA Transcriptome and Global Network Structure in Colorectal Carcinoma after Cetuximab Treatment
Marco Ragusa,Alessandra Majorana,Luisa Statello,Marco Maugeri,Loredana Salito,Davide Barbagallo,Maria Rosa Guglielmino,Laura R Duro,Rosario Angelica,Rosario Caltabiano,Antonio Biondi,Maria Di Vita,Giuseppe Privitera,Marina Scalia,Alessandro Cappellani,E Vasquez,Salvatore Lanzafame,Francesco Basile,Cinzia Di Pietro,Michele Purrello +19 more
TL;DR: The relationship between therapeutic response and modifications of microRNA (miRNA) transcriptome in colorectal cancer (CRC) remains unknown by profiling the expression of 667 miRNAs in 2 human CRC cell lines through TaqMan real-time PCR.
Journal ArticleDOI
Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors
Marco Ragusa,Luisa Statello,Marco Maugeri,Alessandra Majorana,Davide Barbagallo,Loredana Salito,Mariangela Sammito,Manuela Santonocito,Rosario Angelica,Andrea Cavallaro,Marina Scalia,Rosario Caltabiano,Giuseppe Privitera,Antonio Biondi,Maria Di Vita,Alessandro Cappellani,E Vasquez,Salvatore Lanzafame,Elisabetta Tendi,Salvatore Celeste,Cinzia Di Pietro,Francesco Basile,Michele Purrello +22 more
TL;DR: Results contribute to deepen current knowledge on still uncharacterized features of MAPK/ERK pathway, pinpointing new oncomiRs in CRC and allowing their translation into clinical practice and CRC therapy.
Journal ArticleDOI
Expression profile and specific network features of the apoptotic machinery explain relapse of acute myeloid leukemia after chemotherapy
Marco Ragusa,Giuseppe Avola,Rosario Angelica,Davide Barbagallo,Maria Rosa Guglielmino,Laura R Duro,Alessandra Majorana,Luisa Statello,Loredana Salito,Carla Consoli,Maria Grazia Camuglia,Cinzia Di Pietro,Giuseppe Milone,Michele Purrello +13 more
TL;DR: AM genes represent critical nodes for the proper execution of cell death following pharmacological induction in patients and it is proposed that their dysregulation could cause a relapse in apparent CR AML patients.
Journal ArticleDOI
The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma
Cinzia Di Pietro,Marco Ragusa,Davide Barbagallo,Laura R Duro,Maria Rosa Guglielmino,Alessandra Majorana,Rosario Angelica,Marina Scalia,Luisa Statello,Loredana Salito,Luisa Tomasello,Salvo Pernagallo,Salvo Valenti,Vito D'Agostino,Patrizio Triberio,Igor Tandurella,Giuseppe A. Palumbo,Piera La Cava,Viviana Cafiso,Taschia Bertuccio,Maria Santagati,Giovanni Li Destri,Salvatore Lanzafame,Francesco Di Raimondo,Stefania Stefani,Bud Mishra,Michele Purrello +26 more
TL;DR: The comparison of the fourteen mutated AM networks has allowed us to pinpoint the hubs with a general and critical role in tumour development and, conversely, in cell physiology: in particular, some of these had already been used as targets for pharmacological anticancer therapy.