A
Alessandra Majorana
Researcher at University of Catania
Publications - 9
Citations - 385
Alessandra Majorana is an academic researcher from University of Catania. The author has contributed to research in topics: microRNA & TAF1. The author has an hindex of 8, co-authored 9 publications receiving 366 citations.
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Journal ArticleDOI
Specific Alterations of MicroRNA Transcriptome and Global Network Structure in Colorectal Carcinoma after Cetuximab Treatment
Marco Ragusa,Alessandra Majorana,Luisa Statello,Marco Maugeri,Loredana Salito,Davide Barbagallo,Maria Rosa Guglielmino,Laura R Duro,Rosario Angelica,Rosario Caltabiano,Antonio Biondi,Maria Di Vita,Giuseppe Privitera,Marina Scalia,Alessandro Cappellani,E Vasquez,Salvatore Lanzafame,Francesco Basile,Cinzia Di Pietro,Michele Purrello +19 more
TL;DR: The relationship between therapeutic response and modifications of microRNA (miRNA) transcriptome in colorectal cancer (CRC) remains unknown by profiling the expression of 667 miRNAs in 2 human CRC cell lines through TaqMan real-time PCR.
Journal ArticleDOI
Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors
Marco Ragusa,Luisa Statello,Marco Maugeri,Alessandra Majorana,Davide Barbagallo,Loredana Salito,Mariangela Sammito,Manuela Santonocito,Rosario Angelica,Andrea Cavallaro,Marina Scalia,Rosario Caltabiano,Giuseppe Privitera,Antonio Biondi,Maria Di Vita,Alessandro Cappellani,E Vasquez,Salvatore Lanzafame,Elisabetta Tendi,Salvatore Celeste,Cinzia Di Pietro,Francesco Basile,Michele Purrello +22 more
TL;DR: Results contribute to deepen current knowledge on still uncharacterized features of MAPK/ERK pathway, pinpointing new oncomiRs in CRC and allowing their translation into clinical practice and CRC therapy.
Journal ArticleDOI
Involvement of GTA protein NC2beta in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation (vol 7, pg 59, 2008)
C. Di Pietro,Maria Alessandra Ragusa,Davide Barbagallo,Lr Duro,Guglielmino,Alessandra Majorana,Giunta,A.M.C. Rapisarda,Elisa Tricarichi,M Miceli,Rosario Angelica,Agata Grillo,Barbara Banelli,I Defferari,Stefano Forte,Alessandro Laganà,Camillo Bosco,Rosalba Giugno,Alfredo Pulvirenti,Alfredo Ferro,Kh Grzeschik,A. Di Cataldo,Gp Tonini,Massimo Romani,Michele Purrello +24 more
TL;DR: The Open Acce Correction Involvement of GTA protein NC2beta in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation.
Journal ArticleDOI
MIR152, MIR200B, and MIR338, human positional and functional neuroblastoma candidates, are involved in neuroblast differentiation and apoptosis
Marco Ragusa,Alessandra Majorana,Barbara Banelli,Davide Barbagallo,Luisa Statello,Ida Casciano,Maria Rosa Guglielmino,Laura R Duro,Marina Scalia,Gaetano Magro,Cinzia Di Pietro,Massimo Romani,Michele Purrello +12 more
TL;DR: Reconstruction of a NB network comprising MIR152, MIR200B, and MIR338 allowed us to confirm their role in the control of NB cell stemness and apoptosis, suggesting that altered regulation of these MIRs could have a role in NB pathogenesis by interfering with the molecular mechanisms, which physiologically control differentiation and death of neuroblasts.
Journal ArticleDOI
Molecular profiling of human oocytes after vitrification strongly suggests that they are biologically comparable with freshly isolated gametes
Cinzia Di Pietro,Marilena Vento,Maria Rosa Guglielmino,Placido Borzì,Manuela Santonocito,Marco Ragusa,Davide Barbagallo,Laura R Duro,Alessandra Majorana,Adele De Palma,M. R. Garofalo,Elisa Minutolo,Paolo Scollo,Michele Purrello +13 more
TL;DR: The comparison of the molecular profiles demonstrated that the vitrification protocol does not alter the biomolecular quality of oocytes, and this cryopreservation technique might be helpful in preserving women's fertility.