L
Lotta Salminen
Researcher at University of Tampere
Publications - 30
Citations - 871
Lotta Salminen is an academic researcher from University of Tampere. The author has contributed to research in topics: Timolol & Cell culture. The author has an hindex of 16, co-authored 30 publications receiving 828 citations.
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Journal ArticleDOI
Ocular inserts for topical delivery
TL;DR: The advantages, disadvantages and requirement for sucess of ocular inserts, and the few inserts which are available on the market or are being developed by pharmaceutical companies for drug delivery are discussed.
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Review: Systemic Absorption of Topically Applied Ocular Drugs in Humans
TL;DR: It is suggested that systemic absorption of ocular drugs is low during the nasolacrimal passage but occurs during conjunctival and nasal contact, and that plasma drug levels were lower when punctal occlusion was applied.
Journal ArticleDOI
Systemic absorption of topically applied ocular timolol.
TL;DR: The rapid systemic absorption of topically applied ocular timolol observed in this study is consistent with the rapid appearance of the cardiovascular and pulmonary side effects reported in connection with timolOL eye drop therapy.
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Glutamate Uptake is Inhibited by Tamoxifen and Toremifene in Cultured Retinal Pigment Epithelial Cells
TL;DR: The glutamate uptake was a sensitive target for the effects of tamoxifen and toremifene, and disturbances in this function could be considered as one of the possible mechanisms of retinal defects.
Journal ArticleDOI
Comparison of an Immortalized Human Corneal Epithelial Cell Line and Rabbit Corneal Epithelial Cell Culture in Cytotoxicity Testing
Anne Huhtala,Marika Mannerström,Päivi Alajuuma,Sami K Nurmi,Tarja Toimela,Hanna Tähti,Lotta Salminen,Hannu Uusitalo +7 more
TL;DR: The human cell line is a promising in vitro alternative in oculotoxicity testing and the use of serum was found to result in lower toxicity of the compounds in both tests.